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Table 3 The exact situations in which biologics were utilized for JDM. Respondents could answer more than one time. Ten potential respondents did not choose any of the choices

From: Biologic therapies for refractory juvenile dermatomyositis: five years of experience of the Childhood Arthritis and Rheumatology Research Alliance in North America

After failing mtx

5/94 5.3%

After failing CS and mtx

14/94 14.9%

After failing CS, mtx, and IVIG

39/94 41.5%

After failing CS, mtx, IVIG, or IM (AZA, MMF, or CSA)

48/94 51.1%

Systemic JDM with internal organ involvement

10/94 14.9%

Severe ulcerative disease

14/94 14.9%

Other

27/94 14.9%

  1. Abbreviations: mtx oral, subcutaneous, or intravenous methotrexate, CS oral or intravenous corticosteroids, AZA azathioprine, MMF mycophenolate, CSA cyclosporine A