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Fig. 2 | Pediatric Rheumatology

Fig. 2

From: Clinical and MRI outcome of cervical spine lesions in children with juvenile idiopathic arthritis treated with anti-TNFα drugs early in disease course

Fig. 2

MRI of cervical spine (patient #8)(T1 TSE FS sagittal with a contrast medium): a initial MRI (January, 2013) showed an intense contrast enhancement of a huge synovial thickening (white arrow) in predental space with a huge anterior atlanto-axial subluxation (aAAS)(black line, 13 mm) and a compression of the anterior liquor space, normal shape of the dens, b follow-up MR (January, 2014): the evaluation of the treatment with anti-TNFα showed a reduction of synovial thickening and a less intense contrast-enhancement and less significant aAAS, normal width of the anterior liquor space, but with initial morphological changes of the dens, c follow-up MRI (March, 2016): the evaluation of the treatment with anti-TNFα showed a significant reduction of synovial thickening in the predental space and aAAS, only patchy contrast enhancement, but with morphological changes of the dens and a thinned corticalis

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