CTP at time of AE | GC | MTX | IL-1 Inhibitor | IL-6 Inhibitor | Total |
---|---|---|---|---|---|
Grade 2 | 0 | 2 (allergic reaction [1], arthritis flare [1]) | 5 (MAS [1], hepatitis [1], rash [1], Strep pharyngitis [1], injection site reaction [1]) | 8 (fever [1}, rash [1], arthritis flare [2], headache [1], neutropenia [1], viral illness [1], infusion reaction [1]) | 15 |
Grade 3 | 0 | 0 | 2 (infections)b | 0 | 2 |
Grade 4 | 0 | 0 | 0 | 1 (infusion reaction) | 1 |
SAE | 0 | 1a | 2 (infections)b | 1 (MAS) | 3 |