Table 4 Multivariable logistic regression analysis of laboratory data for predicting IVIG-resistant in iKD patients
From: Predictors for intravenous immunoglobulin resistance and coronary artery lesions in Kawasaki disease
Cutoff | OR | p | Sensitivity, % | Specificity, % | PPV, % | NPV, % |
|---|---|---|---|---|---|---|
(95% CI) | (95% CI) | (95% CI) | (95% CI) | (95% CI) | ||
WBC ( × 109/L) | ||||||
>17.56 | 6.032(2.406–15.12) | 0.000 | 64(44.52–79.75) | 77.24(69.07–83.75) | 36.3(23.78–51.13) | 91.35(84.37–95.38) |
>20 | 5.053(2.004–12.736) | 0.000 | 48(30.03–66.5) | 84.55(77.13–89.88) | 38.7(23.73–56.18) | 88.8(81.91–93.39) |
N (%) | ||||||
>70 | 4.303(1.712–10.817) | 0.002 | 68(48.41–82.79) | 66.94(58.15–74.69) | 29.8(19.53–42.66) | 91.0(83.25–95.37) |
>80 | 8.721(3.142–24.21) | 0.000 | 44(26.67–62.93) | 91.74(85.45–95.45) | 52.3(32.37–71.66) | 88.8(82.08–93.21) |
HB (g/L) | ||||||
<110 | 5.25(1.702–16.197) | 0.004 | 80(60.87–91.14) | 54.1(45.27–62.68) | 26.3(17.73–37.18) | 92.9(84.55–96.95) |
CRP (mg/L) | ||||||
>70 | 3.804(1.476–9.803) | 0.006 | 72(52.42–85.72) | 59.66(50.68–68.04) | 27.27(18–39.04) | 91.0(82.62–95.58) |
>100 | 3.776(1.548–9.209) | 0.003 | 56(37.07–73.33) | 74.79(66.3–81.73) | 31.82(20–46.56) | 89(81.37–93.75) |
ESR (mm/h) | ||||||
>80 | 4.675(1.791–12.204) | 0.002 | 70.83(50.83–85.09) | 65.81(56.84–73.78) | 29.8(19.53–42.66) | 91.67(83.78–95.9) |
>100 | 8.154(2.955–22.499) | 0.000 | 45.83(27.89–64.93) | 90.6(83.95–94.67) | 50(30.72–69.28) | 89.08(82.2–93.5) |
ALB (g/L) | ||||||
<32 | 7.5(2.543–22.117) | 0.000 | 42.86(24.47–63.45) | 92.73(86.3–96.27) | 52.9(30.96–73.83) | 89.47(82.5–93.88) |
NT–proBNP (pg/ml) | ||||||
>360 | 4.795(1.252–18.366) | 0.022 | 78.57(52.41–92.43) | 56.67(46.36–66.42) | 22(12.75–35.24) | 94.4(84.89–98.09) |
>1300 | 2.000(0.553–7.231) | 0.29 | 28.57(11.72–54.65) | 83.33(74.31–89.63) | 21.05(8.51–43.33) | 88.2(79.68–93.48) |
IL–6 (pg/ml) | ||||||
>15 | 9.474(2.04–43.995) | 0.004 | 88.24(65.66–96.71) | 55.81(45.29–65.84) | 28.3(17.97–41.57) | 96(86.54–98.9) |
>25 | 4.717(1.516–14.676) | 0.007 | 70.59(46.87–86.72) | 66.28(55.78–75.38) | 29.2(17.61–44.48) | 91.9(82.47–96.51) |
>120 | 15(4.242–53.042) | 0.000 | 52.94(30.96–73.83) | 93.02(85.6–96.76) | 60(35.75–80.18) | 90.9(83.07–95.32) |
IL–10 (pg/ml) | ||||||
>8 | 5.333(1.764–16.125) | 0.003 | 64.71(41.3–82.69) | 74.42(64.29–82.46) | 33.3(19.75–50.39) | 91.4(82.53–96.01) |
>30 | 8.542(2.008–36.328) | 0.001 | 29.41(13.28–53.13) | 95.35(88.64–98.18) | 55.5(26.67–81.12) | 87.23(79-92.54) |