Table 3 Multivariable logistic regression analysis of laboratory data for predicting IVIG-resistant in cKD patients
From: Predictors for intravenous immunoglobulin resistance and coronary artery lesions in Kawasaki disease
Cutoff | OR | p | Sensitivity, % | Specificity, % | PPV, % | NPV, % |
|---|---|---|---|---|---|---|
(95% CI) | (95% CI) | (95% CI) | (95% CI) | (95% CI) | ||
WBC( × 109 L) | ||||||
>13.18 | 7.803(2.327–26.161) | 0.001 | 89.66(69.44–94.50) | 46.32(41.36–51.34) | 11.3(7.83–16.05) | 98.32(95.19–99.43) |
>16 | 3.002(1.412–6.385) | 0.004 | 55.17(37.55–71.59) | 69.47(64.67–73.89) | 12.12(7.6–18.78) | 95.31(92.14–97.24) |
>20 | 4.524(2.017–10.145) | 0.000 | 37.93(22.69–56) | 88.68(85.1–91.49) | 20.37(11.77–32.9) | 94.9(92.13–96.77) |
N (%) | ||||||
>70 | 2.341(1.096–5.001) | 0.028 | 60(42.32–75.41) | 60.42(55.42–65.22) | 10.71(6.89–16.3) | 95.02(91.5–97.13) |
>80 | 4.561(2.117–9.83) | 0.000 | 46.67(30.23–63.86) | 83.91(79.87–87.26) | 18.67(11.46–28.93) | 95.2(92.36–97.03) |
CRP(mg/L) | ||||||
>70 | 4.402(1.644–11.786) | 0.003 | 82.76(65.45–92.4) | 47.84(42.8–52.92) | 11.06(7.55–15.93) | 97.2(93.73–98.82) |
>100 | 3.231(1.46–7.15) | 0.004 | 65.52(47.35–80.06) | 62.7(57.67–67.48) | 12.1(7.89–18.13) | 95.8(92.56–97.74) |
ESR (mm/h) | ||||||
>50 | 2.441(0.908–6.559) | 0.077 | 82.76(65.45–92.4) | 33.71(28.98–38.79) | 9.3(6.33–13.47) | 95.9(90.91–98.27) |
>100 | 2.438(1.055–5.634) | 0.037 | 31.03(17.28–49.23) | 84.42(80.27–87.83) | 14.06(7.58–24.62) | 93.7(90.49–95.89) |
ALB (g/L) | ||||||
<32 | 11.719(4.689–29.288) | 0.000 | 72(52.42–85.72) | 83.19(78.84–86.79) | 24(15.75–34.78) | 97.5(95.09–98.82) |
NT–proBNP(pg/ml) | ||||||
>1300 | 9.189(3.496–24.156) | 0.000 | 73.91(53.53–87.45) | 76.43(71.44–80.79) | 18.68(12–27.9) | 97.5(94.78–98.88) |
IL–6 (pg/ml) | ||||||
>30 | 6.243(1.801–21.637) | 0.004 | 85.71(65.36–95.02) | 50.99(45.38–56.58) | 10.84(6.97–16.49) | 98.0(94.53–99.35) |
>45 | 5.131(1.831–14.381) | 0.002 | 76.19(54.91–89.37) | 61.59(55.99–66.9) | 12.12(7.6–18.78) | 97.3(94.02–98.88) |
>200 | 2.309(0.798–6.683) | 0.123 | 23.81(10.63–45.09) | 88.08(83.94–91.26) | 12.2(5.32–25.54) | 94.3(90.98–96.48) |
IL–10 (pg/ml) | ||||||
>5 | 2.614(0.858–7.96) | 0.091 | 80.95(60–92.33) | 38.08(32.79–43.67) | 8.33(5.27–12.94) | 96.6(91.68–98.69) |
>30 | 6.533(2.481–17.201) | 0.001 | 38.1(20.75–59.12) | 91.39(87.68–94.06) | 23.53(12.44–40) | 95.5(92.46–97.35) |