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Table 3 Medication changes and protocol violations in first 3 months

From: A comparison of three treatment strategies in recent onset non-systemic Juvenile Idiopathic Arthritis: initial 3-months results of the BeSt for Kids-study

 

Arm 1

MTX or SSZ monotherapy

n = 32

Arm 2

Combo MTX+

6 wks prednisone

n = 32

Arm 3

Combo

MTX+ etanercept

n = 30

MTX dose reduction/switch to SC

2

1

2

Switch SSZ to MTX

3/15

NA

NA

Corticosteroids outside of protocol

-kenacort intramuscular

-prednisone orally 4-6wk

3

2

1

0

0

0

0

0

0

Intra articular corticosteroid injections

0

0

0

  1. SSZ sulphasalazine, MTX methotrexate, sc subcutaneous, IM intramuscular, NA not applicable