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Table 2 Demographics, clinical and laboratory features in cTA patients with and without dissection

From: Arterial dissection in childhood Takayasu Arteritis: not as rare as thought

 

cTA with dissection

(N = 3)

cTA without dissection

(N = 24)

P-value

Age at diagnosis in years, mean (SD)

12.4 (2.2)

11.5 (3.7)

0.37

Female (%)

3 (100)

17 (71)

0.55

Tuberculosis (%)

1 (33)

2 (8)

0.29

Arterial hypertension (%)

2 (66)

13 (54)

1

Constitutional symptoms (%)

3 (100)

14 (58)

0.27

PVAS, median (IQR)

21 (8–25)

10 (6–35)

0.26

ESR in mm/h, median (IQR)

32 (31–40)

35 (1–109)

0.89

Albumin in g/L, mean (SD)

32.3 (6.4)

41.1 (6.6)

0.05

Hemoglobin in g/L, mean (SD)

113.7 (31.0)

112.8 (18.4)

0.95

WBC in x109, mean (SD)

13.7 (8.6)

9.3 (3.0)

0.07

Neutrophils in x109, mean (SD)

15.7 (4.8)

5.8 (2.3)

<0.0001

Platelets in x109, mean (SD)

349 (183)

401 (155)

0.60

Imaging at diagnosis (%)

 MRI/A

3 (100)

5 (21)

0.02

 Conventional angiography

0

6 (25)

1

 Combined (MRI/A, CTA, angiography)

0

13 (54)

0.22

  1. Legend: Data are presented as counts with percentages, mean with standard deviation (SD) or median with interquartile range (IQR). Constitutional symptoms included malaise, weight loss, fever and lymphadenopathy. C-reactive protein was not included into the analysis, as the assay method changed during the study period
  2. PVAS pediatric vasculitis activity score, ESR erythrocyte sedimentation rate, WBC white blood cell count, MRI/A magnetic resonance imaging with angiography, CTA computer tomography angiography