Table 4 EULAR/PRINTO/PRES classification criteria for childhood Polyarteritis nodosa (PAN) [23]

Histopathology or angiographic abnormalities (mandatory) plus one of the five following criteria:

- Histology: necrotising vasculitis in medium or small-sized arteries.

- Angiography: aneurysm, stenosis or occlusion of a medium or small sized artery,

EULAR/PRINTO/PRES classification criteria for childhood Polyarteritis nodosa (c-PAN)

1. Skin involvement

Livedo reticularis, skin nodules, superficial ulcers, peripheral tissue necrosis

2. Myalgia/muscle tenderness

Muscle pain or tenderness

3. Hypertension

Blood pressure > 95th centile

4. Peripheral neuropathy

Sensory or motor neuropathy

5. Renal involvement

Proteinuria, haematuria, impaired function