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Table 1 Six patients with Henoch-Schönlein purpura treated with azathioprine

From: Azathioprine therapy for steroid-resistant Henoch-Schönlein purpura: a report of 6 cases

  Demographics Clinical manifestations Duration of disease prior to starting azathioprine Azathioprine dose and duration Glucocorticoid dose and duration Length of remission off all medication
Patient 1 7 y/o female Rash, abdominal pain 5 weeks 1 mg/kg/day for 11 months Discharged on methylprednisolone 1 mg/kg/day tapered over 6 weeks (total of 9 weeks including 3 weeks of inpatient treatment) 15 months
Patient 2 11 y/o female Rash, arthralgias, abdominal pain 7 months 1 mg/kg/day for 7 months Prednisone 0.5 mg/kg/day and taper over 6 weeks 8 months
Patient 3 8 y/o female Rash, arthralgias 5 months 1 mg/kg/day for 13 months Prednisone 0.5 mg/kg/day and taper over 6 weeks 4 years
Patient 4 9 y/o male Rash, arthralgias, abdominal pain 3 months 2 mg/kg/day for 18 months (still active and off steroids for last 6 months) Prednisone 1 mg/kg/day and taper over 14 months N/A
Patient 5 9 y/o male Rash, abdominal pain, renal disease Intermittent disease over 4 years 1 mg/kg/day for 21 months Prednisone 0.5 mg/kg/day and taper over 16 months 3.5 years
Patient 6 8 y/o female Rash, arthralgias, abdominal pain 4 months 1 mg/kg/day for 13 months Prednisone 0.5 mg/kg/day and taper over 6 months 20 months