Table 1 Six patients with Henoch-Schönlein purpura treated with azathioprine
From: Azathioprine therapy for steroid-resistant Henoch-Schönlein purpura: a report of 6 cases
Demographics | Clinical manifestations | Duration of disease prior to starting azathioprine | Azathioprine dose and duration | Glucocorticoid dose and duration | Length of remission off all medication | |
|---|---|---|---|---|---|---|
Patient 1 | 7 y/o female | Rash, abdominal pain | 5 weeks | 1 mg/kg/day for 11 months | Discharged on methylprednisolone 1 mg/kg/day tapered over 6 weeks (total of 9 weeks including 3 weeks of inpatient treatment) | 15 months |
Patient 2 | 11 y/o female | Rash, arthralgias, abdominal pain | 7 months | 1 mg/kg/day for 7 months | Prednisone 0.5 mg/kg/day and taper over 6 weeks | 8 months |
Patient 3 | 8 y/o female | Rash, arthralgias | 5 months | 1 mg/kg/day for 13 months | Prednisone 0.5 mg/kg/day and taper over 6 weeks | 4 years |
Patient 4 | 9 y/o male | Rash, arthralgias, abdominal pain | 3 months | 2 mg/kg/day for 18 months (still active and off steroids for last 6 months) | Prednisone 1 mg/kg/day and taper over 14 months | N/A |
Patient 5 | 9 y/o male | Rash, abdominal pain, renal disease | Intermittent disease over 4 years | 1 mg/kg/day for 21 months | Prednisone 0.5 mg/kg/day and taper over 16 months | 3.5 years |
Patient 6 | 8 y/o female | Rash, arthralgias, abdominal pain | 4 months | 1 mg/kg/day for 13 months | Prednisone 0.5 mg/kg/day and taper over 6 months | 20 months |