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Table 2 The absolute and relative frequencies of most common clinical manifestations in study subjects according to MEFV genotype group

From: Distribution of MEFV gene mutations and R202Q polymorphism in the Serbian population and their influence on oxidative stress and clinical manifestations of inflammation

Clinical manifestations

MEFV mutation carriers (n = 11)

R202Q homozygotes (n = 10)

MEFV/R202Qhomo (n = 20)

Control (n = 76)

Reccurent febrile episodes

8 (72.7 %)*

8 (80 %)*

16 (80 %)**

31 (40.8 %)

Peritonitis

5 (45.5 %)**

3 (30 %)

8 (40 %)**

8 (10.5 %)

Fatigue/malaise

6 (54.5 %)**

4 (40 %)

10 (50 %)**

11 (14.5 %)

Diffuse abdominal pain

7 (63.6 %)*

6 (60 %)*

12 (60 %)**

21 (27.6 %)

Lymphadenopathy

3 (27.3 %)

7 (70 %)*

10 (50 %)

28 (36.8 %)

Oligoarthralgia

5 (45.5 %)

3 (30 %)

8 (40 %)

20 (26.3 %)

Myalgia

3 (27.3 %)

3 (30 %)

6 (30 %)

13 (17.1 %)

  1. Values are shown as n (%)
  2. MEFV/R202Qhomo MEFV mutation carrier plus R202Q homozygotes group, Control N/N and R202Q/N. Data for 4 subjects in control group were missing
  3. *p < 0.05; **p ≤ 0.01 compared to control group
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Pediatric Rheumatology

ISSN: 1546-0096