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Table 2 Comparison of HLA alleles between TMJ arthritis positive and TMJ negative patient groups and control groups

From: HLA II class alleles in juvenile idiopathic arthritis patients with and without temporomandibular joint arthritis

  Alleles of risk OR (p) Protective alleles OR (p)
DRB1     
 Total JIA group (n = 85) versus control (n = 100) DRB1*07:01 7.28(0.000) DRB*18:01 0.10(0.000)
 TMJ arthritis positive group (n = 62) versus control (n = 100) DRB1*13:01 1.88(0.031) DRB1*18:01 0.13(0.001)
DRB1*07:01 8.87(0.000)
 TMJ arthritis negative group (n = 23) versus control (n = 100) DRB1*11:01 2.97(0.002) - -
 TMJ positive (n = 62) versus TMJ negative (n = 23) group - - DRB*12:01 0.35(0.005)
DQB1     
 Total JIA group (n = 85) versus control (n = 100) DQB1*03:03 2.03(0.052) DQB1*06:01 0.20(0.024)
DQB1*05:01 2.10(0.011) DQB1*0602–8 0.56(0.028)
 TMJ arthritis positive group (n = 62) versus control (n = 100) - - - -
 TMJ arthritis negative group (n = 23) versus control (n = 100) DQB1*0301 2.42(0.011) DQB1*0602–8 0.293(0.018)
DQB1*03:03 2.582(0.051)
DQB1*05:01 3.187(0.002)
 TMJ positive (n = 62) versus TMJ negative (n = 23) group - - DQB1*03:01 0.41(0.017)
DQA1     
 Total JIA group (n = 85) versus control (n = 100) - - - -
 TMJ arthritis positive group (n = 62) versus control (n = 100) - - - -
 TMJ arthritis negative group (n = 23) versus control (n = 100) - - DQA1*02:01 0.163(0.046)
 TMJ positive (n = 62) versus TMJ negative (n = 23) group - - DQA1*05:01 0.33(0.009)
  1. OR odds ratio, p < 0,05
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Pediatric Rheumatology

ISSN: 1546-0096