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Table 2 Comparison of HLA alleles between TMJ arthritis positive and TMJ negative patient groups and control groups

From: HLA II class alleles in juvenile idiopathic arthritis patients with and without temporomandibular joint arthritis

 

Alleles of risk

OR (p)

Protective alleles

OR (p)

DRB1

    

 Total JIA group (n = 85) versus control (n = 100)

DRB1*07:01

7.28(0.000)

DRB*18:01

0.10(0.000)

 TMJ arthritis positive group (n = 62) versus control (n = 100)

DRB1*13:01

1.88(0.031)

DRB1*18:01

0.13(0.001)

DRB1*07:01

8.87(0.000)

 TMJ arthritis negative group (n = 23) versus control (n = 100)

DRB1*11:01

2.97(0.002)

-

-

 TMJ positive (n = 62) versus TMJ negative (n = 23) group

-

-

DRB*12:01

0.35(0.005)

DQB1

    

 Total JIA group (n = 85) versus control (n = 100)

DQB1*03:03

2.03(0.052)

DQB1*06:01

0.20(0.024)

DQB1*05:01

2.10(0.011)

DQB1*0602–8

0.56(0.028)

 TMJ arthritis positive group (n = 62) versus control (n = 100)

-

-

-

-

 TMJ arthritis negative group (n = 23) versus control (n = 100)

DQB1*0301

2.42(0.011)

DQB1*0602–8

0.293(0.018)

DQB1*03:03

2.582(0.051)

DQB1*05:01

3.187(0.002)

 TMJ positive (n = 62) versus TMJ negative (n = 23) group

-

-

DQB1*03:01

0.41(0.017)

DQA1

    

 Total JIA group (n = 85) versus control (n = 100)

-

-

-

-

 TMJ arthritis positive group (n = 62) versus control (n = 100)

-

-

-

-

 TMJ arthritis negative group (n = 23) versus control (n = 100)

-

-

DQA1*02:01

0.163(0.046)

 TMJ positive (n = 62) versus TMJ negative (n = 23) group

-

-

DQA1*05:01

0.33(0.009)

  1. OR odds ratio, p < 0,05