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Fig. 3 | Pediatric Rheumatology

Fig. 3

From: IgG4-related disease: a systematic review of this unrecognized disease in pediatrics

Fig. 3

Histology of the orbital tissue of an adult patient from our hospital with IgG4-related orbital disease. a HE-staining demonstrating multiple lymphoid infiltrates and fibrosis. b Immunohistochemical staining for IgG showing diffuse scattered IgG (brown color). c Immunohistochemical staining for IgG4 revealing widely scattered IgG4 positive plasma cells (dark brown) with an average of 339 per HPF out of 2 HPF with a ratio of 0.67 to total IgG plasma cells in the tissue. HE = Hematoxylin and Eosin, HPF = High-power field

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