From: Familial autoimmunity in the childhood arthritis and rheumatology research alliance registry
Outcome | Level | Disease group | P-value | ||
---|---|---|---|---|---|
JIA | SLE | JDM | |||
(N = 4,677) | (N = 639) | (N = 440) | |||
# of autoimmune diseases in family | |||||
Mean ± SD | -- | 0.4 ± 0.8 | 0.4 ± 0.7 | 0.3 ± 0.6 | <0.001 |
Median | 0 | 0 | 0 | ||
(Range) | (0 – 14) | (0 – 5) | (0 – 4) | ||
# of autoimmune diseases in family | 0 | 3189 (66.2 %) | 435 (68.1 %) | 350 (80.8 %) | <0.001 |
1-2 | 1377 (29.4 %) | 192 (30.1 %) | 82 (18.6 %) | ||
3+ | 111 (2.4 %) | 12 (1.9 %) | 8 (1.8 %) |