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Table 4 Association between allergic diseases and risk for juvenile idiopathic arthritis

From: Epidemiology and risk of juvenile idiopathic arthritis among children with allergic diseases: a nationwide population-based study

 

All (N = 1645)

Girls (N = 840)

Boys (N = 805)

Age < 12 (N = 645)a

Age ≥ 12 (N = 1000)a

Allergic diseases

aOR (95 % CI)

aOR (95 % CI)

aOR (95 % CI)

aOR (95 % CI)

aOR (95 % CI)

AC

1.44 (1.07, 1.95)*

1.01 (0.63, 1.62)

1.92 (1.29, 2.87)**

1.69 (1.03, 2.76)*

1.33 (0.91, 1.96)

AR

1.50 (1.15, 1.96)**

1.70 (1.15, 2.50)**

1.36 (0.94, 1.97)

1.40 (0.93, 2.12)

1.59 (1.12, 2.26)**

Asthma

1.44 (1.00, 2.10)*

1.31 (0.74, 2.30)

1.57 (0.95, 2.58)

1.97 (1.19, 3.25)**

1.00 (0.56, 1.82)

AD

1.51 (0.93, 2.47)

2.61 (1.38, 4.96)**

0.74 (0.32, 1.71)

1.95 (1.05, 3.62)*

1.00 (0.43, 2.33)

Number of concurrent allergic disease

 0

1.00 (reference)

1.00 (reference)

1.00 (reference)

1.00 (Reference)

1.00 (Reference)

 1

1.50 (1.12, 2.01)**

1.69 (1.13, 2.53)*

1.34 (0.88, 2.05)

1.12 (0.61, 2.07)

1.29 (0.71, 2.35)

 2+

1.72 (1.24, 2.38)**

1.56 (0.95, 2.57)

1.84 (1.19, 2.86)**

1.42 (0.81, 2.50)

2.54 (1.42, 4.54)**

P for trend

<0.001

0.02

0.006

0.002

0.04

  1. Abbreviations: AC allergic conjunctivitis, AR allergic rhinitis, AD atopic dermatitis, OR odds ratio, CI 95 % confidence interval
  2. aThe age is partitioned into two sub-segments (<12 vs. ≥12 years) based on mean age
  3. *P < 0.05, **P < 0.01