Table 1 Distribution of genotypes IL-12p40 pro 1.1, IL-12p40 pro 1.2, IL-12p40 pro 2.2 and of alleles IL-12p40 pro 1 and IL-12p40 pro 2 in patients with a subtype of JIA and healthy controls (absolute number and percentage), all in Hardy-Weinberg equilibrium
From: No association of IL-12p40 pro1.1 polymorphism with juvenile idiopathic arthritis
No of patients (% of JIA) | IL-12 p40 pro1.1 | IL-12 p40 pro1.2 | IL-12 p40 pro2.2 | Chi2-test p-value | |
|---|---|---|---|---|---|
Polyarthritis RF positive | 29 (3.3 %) | 6 (20 %) | 12 (41 %) | 11 (37.9 %) | 0.2306 |
Polyarthritis RF negative | 151 (17.1 %) | 46 (30.46 %) | 70 (46.36 %) | 35 (23.17 %) | 0.7842 |
Systemic arthritis | 139 (15.7 %) | 45 (32.4 %) | 64 (46.0 %) | 30 (21.6 %) | 0.556 |
Oligoarthritis | 469 (58.1 %) | 102 (21,75 %) | 246 (52.45 %) | 121 (25,8 %) | 0.1866 |
Psoriasis-related arthritis | 29 (3.3 %) | 7 | 15 | 7 | 0.92 |
Enthesitis-related arthritis | 52 (5.9 %) | 9 (17 %) | 32 (61 %) | 11 (21 %) | 0.1932 |
Undifferentiated arthritis | 14 (1.6 %) | 4 | 7 | 3 | |
All patients with JIA | 883 | 219 (24.8 %) | 446 (50.5 %) | 218 (24.7 %) | 0.654 |
Healthy individuals | 321 | 88 (27.4 %) | 157 (48.9 %) | 76 (23.7 %) | |
Allele pro 1 | JIA | 884 (50.1 %) | 0.432 | ||
Healthy Controls | 333 (51.9 %) | ||||
Allele pro 2 | JIA | 882 (49.9 %) | |||
Healthy Controls | 309 (48.1 %) | ||||