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Table 2 Details of the 3 girls affected with juvenile idiopathic arthritis that were diagnosed with latent tuberculosis infection and received antituberculosis chemoprophylaxis

From: Tuberculosis in pediatric patients treated with anti-TNFα drugs: a cohort study

Pt Age - gender – primary disease TST (mm) Treatment at QTF-G performance QTF-G IFN-γ concentrations (TB antigens-nil) LTBI chemoprophylaxis Maximum ALT/AST (IU/L) Time on anti-TNFα drugs (before/after LTBI chemoprophylaxis)
1 11y6m – female-
polyarticular JIA, negative RF
0 ETN + MTX 0.55 IU/mL H for 9 months 30/37 22 (1/24) months
2 10y7m – female -
oligoarticular JIA
0 ETN 0.37 IU/mL HR for 3 months 31/38 29 (14/25) months
3 8y5m – female -
oligoarticular JIA
15 NSAIDs 4.78 IU/mL HR for 3 months 25/24 12 (0/29) months
  1. ALT alanine aminotransferase, AST aspartate aminotransferase, H isoniazid, IFN-γ interferon-gamma, MTX methotrexate, NSAIDs non-steroidal anti-inflammatory drugs, Pt patient, R rifampicin, RF rheumatoid factor