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Table 2 Details of the 3 girls affected with juvenile idiopathic arthritis that were diagnosed with latent tuberculosis infection and received antituberculosis chemoprophylaxis

From: Tuberculosis in pediatric patients treated with anti-TNFα drugs: a cohort study

Pt

Age - gender – primary disease

TST (mm)

Treatment at QTF-G performance

QTF-G IFN-γ concentrations (TB antigens-nil)

LTBI chemoprophylaxis

Maximum ALT/AST (IU/L)

Time on anti-TNFα drugs (before/after LTBI chemoprophylaxis)

1

11y6m – female-

polyarticular JIA, negative RF

0

ETN + MTX

0.55 IU/mL

H for 9 months

30/37

22 (1/24) months

2

10y7m – female -

oligoarticular JIA

0

ETN

0.37 IU/mL

HR for 3 months

31/38

29 (14/25) months

3

8y5m – female -

oligoarticular JIA

15

NSAIDs

4.78 IU/mL

HR for 3 months

25/24

12 (0/29) months

  1. ALT alanine aminotransferase, AST aspartate aminotransferase, H isoniazid, IFN-γ interferon-gamma, MTX methotrexate, NSAIDs non-steroidal anti-inflammatory drugs, Pt patient, R rifampicin, RF rheumatoid factor