Table 4 Phenotype-genotype correlation
From: The common NOD2/CARD15 variant P268S in patients with non-infectious uveitis: a cohort study
No mutation | He | Ho | p-value | |
|---|---|---|---|---|
P268/SNP5 | P268/SNP5 | |||
Comorbility, % (n) | 5 | 9 | 50 % (1) | n.s. |
Positive family history, % (n) | 1 | 4 | 50 % (1) | n.s. |
Granulomatous uveitis, % (n) | 0 | 5 | 0 | n.s. |
Panuveitis, % (n) | 3 | 9 | 0 | n.s. |
Bilateral uveitis, % (n) | 6 | 8 | 50 % (1) | n.s. |
ANA positive, % (n) | 3 | 7 | 50 % (1) | n.s. |
HLA B27 positive, % (n) | 0 | 2 | 0 | n.s. |
Macular edema, % (n) | 3 | 7 | 0 | n.s. |
Synechiae, % (n) | 2 | 4 | 1 | n.s. |
Glaucoma, % (n) | 2 | 2 | 0 | n.s. |
Visual loss, % (n) | 2 | 3 | 0 | n.s. |
Cataract, % (n) | 2 | 1 | 0 | n.s. |
He = heterozygous; Ho = homozygous | n.s. |