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Table 1 Reported Cases of coexistent pulmonary hemorrhage and venous thromboembolism in patients with AAV

From: Concurrent pulmonary hemorrhage and deep vein thrombosis in a child with ANCA-associated vasculitis: case report and review of literature

No.

Author

Age/Sex

Involved organ

ANCA

Presentation

Steroid (total dose)

CYC

Other agent

PLEX (N sessions)

AC

IVC filter

Outcome

1

Sousa et al. [7]

48(F)

Renal, ENT

PR3-ANCA

Simultaneous PH and PE

Y(1g)

No

MMF

Y(5)

No

Y

Survived, Recurrent PE, Long term AC

2

Sousa et al. [7]

19(F)

Renal, ENT

PR3-ANCA

Simultaneous PH and multiple PE’s, Upper limb DVT

Y(3g)

Y

No

No

UFH

No

Survived, Short-term AC

3

Sousa et al. [7]

61(M)

Renal, ENT, CNS, Skin

MPO-ANCA

PH 2 weeks after multiple PE’s

Y(3g)

No

Rituximab, IVIG

Y(5)

LMWH

Y

Survived, Pulmonary fibrios, Short term AC

4

Sousa et al. [7]

45(M)

Renal, ENT

PR3-ANCA

PH 1 week before multiple PE’s and Lower limb DVT

Y(3g)

Y

No

No

LMWH

Y

Survived, CKD stage 3, Long term AC

5

Dreyer et al. [8]

31(M)

Renal

PR3-ANCA

PH 1 week after Lower limb DVT and PE

Y(1.5g)

Y

No

Y(5)

UFH

Y

Survived, Short-term AC

6

Our case

14(F)

Renal, Skin

MPO-ANCA

PH 5 days after right lower limbs DVT

Y(3g)

Y

MMF

Y(5)

LMWH

N

Survived, Short-term AC

  1. M, male; F, female; Y, yes; ENT, ear, nose and throat; CNS, central nervous system; PE, pulmonary embolism; PH, pulmonary hemorrhage; DVT, deep vein thrombosis; CYC, cyclophosphamide; MMF, mycophenolate mofetil; IVIG, intravenous immunoglobulin; PLEX, plasmapheresis; UFH, unfractioned heparin; LMWH, low molecular weight heparin; AC, anticoagulant; IVC filter, inferior vena cava filter; CKD, chronic kidney disease