Skip to main content

Table 1 Univariable analysis on APPLE data at baseline to 3 years

From: Avascular necrosis in pediatric systemic lupus erythematosus: a brief report and review of the literature

Variable No AVN AVN P-value
No (%) Median (25th, 75th) No (%) Median (25th, 75th)
Baseline 25(OH)D (ng/mL) 25.9 (18.9, 31.6) 18.7 (15.1, 32.2) 0.266
25(OH)D < 20 ng/mL 52/184 (28.3%) 9/17 (52.9%) 0.034
Minority status: non-Caucasian 113/184 (61.4%) 15/17 (88.2%) 0.028
Age (years) 15.5 (13.7, 17.6) 16.5 (14.5, 18.0) 0.207
Female 153/184 (83.2%) 14/17 (82.4%) >0.999
SLE duration (months) 23.5 (8.0, 44.5) 25.0 (7.0, 45.0) 0.787
SLEDAI 4.0 (2.0, 6.0) 4.0 (0.0, 8.0) 0.779
History of hypertension 55/178 (30.9%) 10/17 (58.8%) 0.020
History of glomerulonephritis 58/183 (31.7%) 12/17 (70.6%) 0.001
History of nephritis/nephrosis 67/183 (36.6%) 14/17 (82.4%) <0.001
Corticosteroid use 148/183 (80.9%) 15/17 (88.2%) 0.744
Triglycerides (mg/dL) 99.5 (74, 130.0) 145.5 (88.5, 161.0) 0.050
Total cholesterol (mg/dL) 146.0 (124.0, 173.0) 160.5 (145.5, 183.0)f 0.101
C3 (mg/dL) 99.0 (85.0, 122.0) 108.5 (99.5, 115.0) 0.175
C4 (mg/dL) 13.7 (9.0, 19.) 19.3 (15.1, 22.9) 0.017
Baseline Homocysteine (mcmol/L) 6.7 (5.6, 8.7) 6.8 (5.4, 10.0) 0.538
Latitude (°N) 40.7 (37.4, 40.9) 37.4 (36.0, 40.0) 0.004