Increased soluble phagocytic receptors sMer, sTyro3 and sAxl and reduced phagocytosis in Juvenile-onset Systemic Lupus Erythematosus

Table 2 Phagocytosis of control and JSLE monocytes in 10% JSLE, JIA and control serum

(A) Control CD14 ⁺ cells % Phagocytosis			( B) JSLE CD14 ⁺ cells % Phagocytosis
Control serum	JSLE serum	JIA serum	Control serum	JSLE serum	JIA serum
36.7	9.2	34.1	39.5	33.2	21.2
83.6	72.1	81.81	35.8	18.7	62.4
74.72	63.2	69.3	21.6	11.8	20.7
43.73	29.81	42.78	71.1	34.2	64.4
68.3	61.4	76.72	84.81	83.14	93.44
			14.31	9.05	12.8

This table presents the percentage phagocytosis of 5 control and 6 JSLE monocytes represented in Figure 1C and D. Control and JSLE monocytes were incubated with E coli and either 10% control serum, JSLE or JIA serum. The percentage of phagocytosis was lower when incubated with JSLE serum which was increased following incubation with control or JIA serum.

ISSN: 1546-0096