Skip to main content

Table 1

From: Various aspects of Kikuchi disease in three children: systemic or self-limited disease?

 

Patient 1

Patient 2

Patient 3

Age (years)

5

17

9

Underlying disease

Non complicated sickle cell anemia

Severe sickle cell anemia

None

Symptoms

- Left cervical lymphadenopathy

- Intermittent fever

- Intermittent fever

- Maculo-papules

- Fatigue

- Painful cervical and inguinal adenopathies

- Headaches

- Polyarthritis

- Prolonged fever

- Intermittent tonsillitis

- Bilateral painful cervical lymph nodes

Biological features

- Mild inflammation

- Elevated LDH

- Marked inflammation

- Pancytopenia

- Auto-immune anemia

- Auto-immune hepatitis

- No ANA

- Marked inflammation

- Leucopenia

Biopsy

Cervical lymph node excisional biopsy

Cervical lymph node excisional biopsy

Tonsillectomy

Treatment

None

- Steroids for 7 months

- Azathioprine

- Methotrexate

None

Outcome

Spontaneous resolution after 4 months

Progressive regression of clinical and biological signs with resolution of auto-immunity

Spontaneous resolution 2 months after tonsillectomy