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Table 2

From: Auto-antibody testing for children on biologic therapies for rheumatological conditions: results of audit

Antibody

No of children with positive results / No children with antibodies checked [%]

No of positive antibodies / No antibodies checked [%]

Comments

ANA

80 / 111 [72%]

431 / 540 [79%]

36 children [32%] ANA always +ve; 44 children ANA sometimes +ve but not always.

Anti ENA

4 / 109 [<4%]

18 / 501 [<4%]

Always non-specific. Negative on subsequent testing.

Anti dsDNA

1/ 111 [<1%]

2 / 510 [<1%]

Negative on subsequent testing.

ANCA

14 / 41 [34%]

25 / 66 [38%]

Always non-specific (non PR3 / MPO).

Anticardiolipin

6 / 98 [6%]

8 / 894 [<1%]

Negative on subsequent testing.