Table 1 Canakinumab doses by phenotypes
Phenotype (n=WP/JP) | Wester population | Japanese population | ||
|---|---|---|---|---|
Adult1 Mean/median (mg) (N=136) | Pediatrics2 Mean/mdeian (mg/kg) (N=29) | Adult1 Mean/median (mg) (N=8) | Pediatrics2 Mean/mdeian (mg/kg) (N=11) | |
MWS (103/7) | 200/150 | 5.5/4.0 | 225/150 | 6.0/6.0 |
NOMID (32/11) | 299/150 | 5.8/4.0 | 300/225 | 5.5/6.0 |
FCAS (30/0) | 189/150 | 2.7/2.0 | - | - |