Corticosteroid-induced spinal epidural lipomatosis in the pediatric age group: report of a new case and updated analysis of the literature

Table 1 Demographic and clinical characteristics of the patients.

Pt.	Age (years)	Sex	Diagnosis	Duration of steroid treat- ment (years)	Steroid dose (mg/d)	Therapy	Clinical outcome^a	Reference
1	17 (?)^b	m	Kidney transplant	1	40	Surgery SR	Improvement	Lee 1975 [1]
2	13	m	Kidney transplant	1.5	45	SR, diet	Resolution	George 1983 [5]
3	6	m	JIA	4	40	Surgery SR	Improvement	Perling 1988 [6]
4	11	m	Pineoblastoma	1	20	Surgery	Progression of symptoms due to spread of tumor	Quint 1988 [7]
5	6	m	sJIA	1	10-40	Surgery	Resolution	Arroyo 1988 [8]
6	16	m	Kidney transplant	3	0.4/kg	SR, diet	Resolution	Vazquez 1988 [9]
7	10	m	NS	0.7	60	SR, diet	Improvement	Shirai 1990 [10]
8	11	m	NS	0.8	12-60	Surgery	Improvement	Kano 1996 [15]^c
9	14	f	NS	0.25	24-80	SR	Resolution	-„-
10	14	m	NS	0.4	48-80	SR	Resolution	-„-
11	10	m	HSP	0.8	36-72	SR	Resolution	-„-
12	8	f	Crohn disease	6.5	10-60?	SR	Died from sepsis	Muňoz 2002 [11]
13	14	m	SLE	0.8	<60	SR	Improvement	Miller 2002 [12]
14	5	f	NS	1.4	5-60	SR	Resolution	Kano 2004, 2005 [13, 16]
15	10	f	NS	0.4	20-60	SR	Resolution	Kano 2005 [16]
16	14	f	SLE	0.5	0.2/kg	SR	Resolution	Möller 2010 [17]
17	11	f	Sjögren syndrome	0.6	0.5/kg	SR	Resolution	Möller 2010 [17]
18	7	f	sJIA	1.5	40	SR	Resolution^d	Möller 2010 [17]
19	12	f	Lung transplant	0.06	25	SR, diet	Resolution	Caruba 2010 [14]
20	10	f	Relapsing polychondritis	0.4	30	SR	Resolution	This report

^aImprovement or resolution as interpreted from the authors' reports of symptoms, findings or imaging.
^bAge could not be determined accurately, but was more likely 17 than 18 years.
^cPatient diagnosed in 1979.
^dDied from chronic macrophage activation syndrome 1 year later.
Abbreviations: f, female; HSP, Henoch Schönlein purpura; LE, lower extremity; m, male; n/d, not done or not documented; NS, nephrotic syndrome; sJIA, systemic juvenile idiopathic arthritis; SLE, systemic lupus erythematosus; SR, steroid reduction; UE, upper extremity.

ISSN: 1546-0096