From: Post-streptococcal reactive arthritis in children: a distinct entity from acute rheumatic fever
 | The five major manifestations are |
---|---|
1 | Polyarthritis (predominantly involving the large joints) |
2 | Carditis, valvulitis and pericarditis (eg, pancarditis) |
3 | Central nervous system involvement (eg, Sydenham chorea) |
4 | Erythema marginatum |
5 | Subcutaneous nodules |
 | The four minor manifestations are |
1 | Arthralgia |
2 | Fever |
3 | Elevated acute phase reactants [erythrocyte sedimentation rate (ESR), C-reactive protein (CRP)] |
4 | Prolonged PR interval |