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Table 1 Jones criteria for the diagnosis of acute rheumatic fever (ARF)

From: Post-streptococcal reactive arthritis in children: a distinct entity from acute rheumatic fever

  The five major manifestations are
1 Polyarthritis (predominantly involving the large joints)
2 Carditis, valvulitis and pericarditis (eg, pancarditis)
3 Central nervous system involvement (eg, Sydenham chorea)
4 Erythema marginatum
5 Subcutaneous nodules
  The four minor manifestations are
1 Arthralgia
2 Fever
3 Elevated acute phase reactants [erythrocyte sedimentation rate (ESR), C-reactive protein (CRP)]
4 Prolonged PR interval
  1. Supporting evidence of antecedent group A streptococcal infection,»
  2. Postive throat culture or rapid streptococcal antigen test
  3. Elevated or rising streptococcal antibody liter