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Table 3 Arthritis activity markers in JIA girls with polymorphic GR genotypes.

From: Glucocorticoid receptor gene polymorphism and juvenile idiopathic arthritis

Parameter CC GC GG p1 p2 p3
Onset age, years 9.07 ± 4.9 6.9 ± 4.8 5.38 ± 3.1 0.04 0.09 0.0017
Morning stiffness, min 66.2 ± 75.0 103.4 ± 85.8 129.0 ± 98.5 0.03 0.19 0.02
SJC 5.53 ± 6.74 6.03 ± 7.2 11.8 ± 14.1 0.39 0.07 0.06
TJC 7.03 ± 8.0 7.8 ± 6.72 14.7 ± 20.3 0.37 0.11 0.09
VAS, mm 36.3 ± 20.8 39.0 ± 22.4 55.0 ± 27.5 0.02 0.03 0.014
RAI 12.37 ± 14.3 15.3 ± 19.1 23.9 ± 23.4 0.24 0.11 0.048
DAS 2.97 ± 1.7 5.3 ± 1.7 4.3 ± 2.4 0.25 0.07 0.035
DAS 28 3.44 ± 1.5 3.77 ± 1.4 4.3 ± 1.7 0.19 0.14 0.05
Hemoglobin, g/l 123.0 ± 14.5 119.8 ± 14.3 118.5 ± 15.6 0.18 0.39 0.18
Leukocytes, ×109/l 7.61 ± 2.26 8.78 ± 3.2 8.66 ± 2.5 0.046 0.45 0.09
Platelets, ×109/l 232.3 ± 60.2 283.5 ± 83.8 286.3 ± 95.3 0.003 0.46 0.03
ESR, mm/h 14.5 ± 19.3 14.3 ± 14.7 15.6 ± 15.3 0.48 0.39 0.42
CRP, mg/l 4.0 ± 9.6 19.3 ± 37.5 18.4 ± 30.8 0.01 0.46 0.048
Albumin, % 55.5 ± 6.9 51.5 ± 8.5 50.9 ± 8.5 0.02 0.41 0.04
  1. р1 - comparison between carriers СС and GC genotypes
  2. р2 - comparison between carriers GC and GG genotypes
  3. р3 - comparison between carriers СС and GG genotypes