Table 3 Arthritis activity markers in JIA girls with polymorphic GR genotypes.
From: Glucocorticoid receptor gene polymorphism and juvenile idiopathic arthritis
Parameter | CC | GC | GG | p1 | p2 | p3 |
|---|---|---|---|---|---|---|
Onset age, years | 9.07 ± 4.9 | 6.9 ± 4.8 | 5.38 ± 3.1 | 0.04 | 0.09 | 0.0017 |
Morning stiffness, min | 66.2 ± 75.0 | 103.4 ± 85.8 | 129.0 ± 98.5 | 0.03 | 0.19 | 0.02 |
SJC | 5.53 ± 6.74 | 6.03 ± 7.2 | 11.8 ± 14.1 | 0.39 | 0.07 | 0.06 |
TJC | 7.03 ± 8.0 | 7.8 ± 6.72 | 14.7 ± 20.3 | 0.37 | 0.11 | 0.09 |
VAS, mm | 36.3 ± 20.8 | 39.0 ± 22.4 | 55.0 ± 27.5 | 0.02 | 0.03 | 0.014 |
RAI | 12.37 ± 14.3 | 15.3 ± 19.1 | 23.9 ± 23.4 | 0.24 | 0.11 | 0.048 |
DAS | 2.97 ± 1.7 | 5.3 ± 1.7 | 4.3 ± 2.4 | 0.25 | 0.07 | 0.035 |
DAS 28 | 3.44 ± 1.5 | 3.77 ± 1.4 | 4.3 ± 1.7 | 0.19 | 0.14 | 0.05 |
Hemoglobin, g/l | 123.0 ± 14.5 | 119.8 ± 14.3 | 118.5 ± 15.6 | 0.18 | 0.39 | 0.18 |
Leukocytes, ×109/l | 7.61 ± 2.26 | 8.78 ± 3.2 | 8.66 ± 2.5 | 0.046 | 0.45 | 0.09 |
Platelets, ×109/l | 232.3 ± 60.2 | 283.5 ± 83.8 | 286.3 ± 95.3 | 0.003 | 0.46 | 0.03 |
ESR, mm/h | 14.5 ± 19.3 | 14.3 ± 14.7 | 15.6 ± 15.3 | 0.48 | 0.39 | 0.42 |
CRP, mg/l | 4.0 ± 9.6 | 19.3 ± 37.5 | 18.4 ± 30.8 | 0.01 | 0.46 | 0.048 |
Albumin, % | 55.5 ± 6.9 | 51.5 ± 8.5 | 50.9 ± 8.5 | 0.02 | 0.41 | 0.04 |