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Table 5 Summary of reported case series of paediatric patients with ANCA vasculitis

From: Long- term outcome of paediatric patients with ANCA vasculitis

MPA

n

M:F

Age

CKD

ESRD

Relapse rate

Rx

Deaths

Bakkalogou [12]

10

4:6

Median: 12 years

(8- 17)

4

(40%)

4

(40%)

5 episodes

Steroids

Oral CP

0

(0%)

Peco- Antic [11]

7

1:6

Mean: 12 years

(7- 15)

1

(14%)

2

(29%)

Not stated

Oral steroids

Oral CP

0

(0%)

Total MPA

17

5:12

7- 17 years

5

(29%)

6

(35%)

Not stated

-

0

(0%)

WG

n

M:F

Age

CKD

ESRD

Relapse rate

Rx

Deaths

Rottem [3]

23

7:16

Mean: 15.4 years

(9- 19)

8

(35%)

2

(9%)

53% of all children and 38% of those with f/u > 5years had > 1 relapse

Oral pred and oral CP

2

(9%)

Stegmayr [6]

10

5:5

11- 30 years

6

(60%)

1

(10%)

Median: 28 months in 80%

9/10 patients received CP and steroids

0

(0%)

Belostotsky [9]

17

4:13

Mean: 6 years

Median: 6.3 years

(2 weeks - 14 years)

3

(18%)

0

(0%)

Not stated

All but one patient received CP + Pred.

Pred in all patients

2

(12%)

Wong [10]

12

4:8

2 months to 14 years

Not stated

Not stated

Not stated

Not stated

Not stated

Total WG

62

20:42

2 weeks to 30 years

17

(27%)

3

(5%)

Not stated

-

-

AAV + Necrotising GN

n

M:F

Age

CKD

ESRD

Relapse rate

Rx

Deaths

Valentini [13]

7

2:5

13 years

(+/- 0.9)

2

(29%)

1

(14%)

Not stated

IV MP + IV CP in all patients

0

(0%)

Grand total

86

27: 59

2 weeks- 30years

24

(28%)

11

(12%)

-

-

-