From: Long- term outcome of paediatric patients with ANCA vasculitis
MPA | n | M:F | Age | CKD | ESRD | Relapse rate | Rx | Deaths |
---|---|---|---|---|---|---|---|---|
Bakkalogou [12] | 10 | 4:6 | Median: 12 years (8- 17) | 4 (40%) | 4 (40%) | 5 episodes | Steroids Oral CP | 0 (0%) |
Peco- Antic [11] | 7 | 1:6 | Mean: 12 years (7- 15) | 1 (14%) | 2 (29%) | Not stated | Oral steroids Oral CP | 0 (0%) |
Total MPA | 17 | 5:12 | 7- 17 years | 5 (29%) | 6 (35%) | Not stated | - | 0 (0%) |
WG | n | M:F | Age | CKD | ESRD | Relapse rate | Rx | Deaths |
Rottem [3] | 23 | 7:16 | Mean: 15.4 years (9- 19) | 8 (35%) | 2 (9%) | 53% of all children and 38% of those with f/u > 5years had > 1 relapse | Oral pred and oral CP | 2 (9%) |
Stegmayr [6] | 10 | 5:5 | 11- 30 years | 6 (60%) | 1 (10%) | Median: 28 months in 80% | 9/10 patients received CP and steroids | 0 (0%) |
Belostotsky [9] | 17 | 4:13 | Mean: 6 years Median: 6.3 years (2 weeks - 14 years) | 3 (18%) | 0 (0%) | Not stated | All but one patient received CP + Pred. Pred in all patients | 2 (12%) |
Wong [10] | 12 | 4:8 | 2 months to 14 years | Not stated | Not stated | Not stated | Not stated | Not stated |
Total WG | 62 | 20:42 | 2 weeks to 30 years | 17 (27%) | 3 (5%) | Not stated | - | - |
AAV + Necrotising GN | n | M:F | Age | CKD | ESRD | Relapse rate | Rx | Deaths |
Valentini [13] | 7 | 2:5 | 13 years (+/- 0.9) | 2 (29%) | 1 (14%) | Not stated | IV MP + IV CP in all patients | 0 (0%) |
Grand total | 86 | 27: 59 | 2 weeks- 30years | 24 (28%) | 11 (12%) | - | - | - |