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Table 5 Summary of reported case series of paediatric patients with ANCA vasculitis

From: Long- term outcome of paediatric patients with ANCA vasculitis

MPA n M:F Age CKD ESRD Relapse rate Rx Deaths
Bakkalogou [12] 10 4:6 Median: 12 years
(8- 17)
4
(40%)
4
(40%)
5 episodes Steroids
Oral CP
0
(0%)
Peco- Antic [11] 7 1:6 Mean: 12 years
(7- 15)
1
(14%)
2
(29%)
Not stated Oral steroids
Oral CP
0
(0%)
Total MPA 17 5:12 7- 17 years 5
(29%)
6
(35%)
Not stated - 0
(0%)
WG n M:F Age CKD ESRD Relapse rate Rx Deaths
Rottem [3] 23 7:16 Mean: 15.4 years
(9- 19)
8
(35%)
2
(9%)
53% of all children and 38% of those with f/u > 5years had > 1 relapse Oral pred and oral CP 2
(9%)
Stegmayr [6] 10 5:5 11- 30 years 6
(60%)
1
(10%)
Median: 28 months in 80% 9/10 patients received CP and steroids 0
(0%)
Belostotsky [9] 17 4:13 Mean: 6 years
Median: 6.3 years
(2 weeks - 14 years)
3
(18%)
0
(0%)
Not stated All but one patient received CP + Pred.
Pred in all patients
2
(12%)
Wong [10] 12 4:8 2 months to 14 years Not stated Not stated Not stated Not stated Not stated
Total WG 62 20:42 2 weeks to 30 years 17
(27%)
3
(5%)
Not stated - -
AAV + Necrotising GN n M:F Age CKD ESRD Relapse rate Rx Deaths
Valentini [13] 7 2:5 13 years
(+/- 0.9)
2
(29%)
1
(14%)
Not stated IV MP + IV CP in all patients 0
(0%)
Grand total 86 27: 59 2 weeks- 30years 24
(28%)
11
(12%)
- - -