Side Effect number reported, (% of total) | Traditional (n = 99) | COX-2 (n = 95) | p-value |
---|---|---|---|
Abdominal Pain | 80 (81) | 22 (23) | < .001 |
Gastric/duodenal ulcer | 6 (6) | 2 (2) | 0.28 |
Hematuria | 4 (4) | 1 (1) | 0.37 |
Hypertension | 3 (3) | 3 (3) | 1.0 |
Thrombocytopenia | 1 (1) | 0 (0) | 1.0 |
Epistaxis | 13 (13) | 2 (2) | .006 |
Easy Bruising | 63 (64) | 8 (8) | < .001 |
Headache | 21 (21) | 1 (1) | < .001 |
Fatigue | 12 (12) | 1 (1) | .003 |