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Table 1 Demographic Data, Laboratory and Clinical Features

From: Autoimmune thyroiditis in antinuclear antibody positive children without rheumatologic disease

  Positive Thyroid Antibodies
(n = 31)
Negative Thyroid Antibodies
(n = 73)
Total
(n = 104)
Demographic features    
   Female (% within group) 30 (97) 61 (84) 91 (88)
   Caucasian (%) 29 (94) 68 (93) 97 (93)
   Age at first visit (yr) ± SD 12.9 ± 3.1 11.6 ± 4.2 11.9 ± 4.0
Family history autoimmune disease    
   1st degree relative (%) 11 (35) 14 (19) 25 (24)
   1st or 2nd degree relative (%) 19 (61) 35 (48) 54 (52)
ANA pattern    
   Homogenous (%) 13 (42) 25 (34) 38 (37)
   Speckled (%) 17 (55) 45 (62) 62 (60)
   Nucleolar (%) 1 (3) 2 (3) 3 (3)
Clinical manifestations    
   Arthralgia (%) 10 (32) 44 (60) 54 (52)
   Rash (%) 3 (10) 9 (12) 12 (11)
   Vitiligo (%) 4 (13) 2 (3) 6 (6)
   Alopecia (%) 3 (10) 2 (3) 5 (5)
   Fatigue (%) 2 (6) 6 (8) 8 (8)
   Miscellaneous (%) 9 (29) 10 (14) 19 (18)
  1. * none of the calculated p-values < 0.05
  2. Autoimmune diseases include: autoimmune thryoiditis (Hashimoto's thyroiditis), Grave's disease, rheumatoid arthritis, insulin-dependent diabetes mellitus, ulcerative colitis, Crohn's disease, systemic lupus erythematosus, psoriasis, multiple sclerosis
  3. Miscellaneous manifestations include: myalgia, urticaria, thrombocytopenia, acrocyanosis