From: Autoimmune thyroiditis in antinuclear antibody positive children without rheumatologic disease
Positive Thyroid Antibodies (n = 31) | Negative Thyroid Antibodies (n = 73) | Total (n = 104) | |
---|---|---|---|
Demographic features | |||
Female (% within group) | 30 (97) | 61 (84) | 91 (88) |
Caucasian (%) | 29 (94) | 68 (93) | 97 (93) |
Age at first visit (yr) ± SD | 12.9 ± 3.1 | 11.6 ± 4.2 | 11.9 ± 4.0 |
Family history autoimmune disease † | |||
1st degree relative (%) | 11 (35) | 14 (19) | 25 (24) |
1st or 2nd degree relative (%) | 19 (61) | 35 (48) | 54 (52) |
ANA pattern | |||
Homogenous (%) | 13 (42) | 25 (34) | 38 (37) |
Speckled (%) | 17 (55) | 45 (62) | 62 (60) |
Nucleolar (%) | 1 (3) | 2 (3) | 3 (3) |
Clinical manifestations | |||
Arthralgia (%) | 10 (32) | 44 (60) | 54 (52) |
Rash (%) | 3 (10) | 9 (12) | 12 (11) |
Vitiligo (%) | 4 (13) | 2 (3) | 6 (6) |
Alopecia (%) | 3 (10) | 2 (3) | 5 (5) |
Fatigue (%) | 2 (6) | 6 (8) | 8 (8) |
Miscellaneous‡ (%) | 9 (29) | 10 (14) | 19 (18) |