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Figure 1 | Pediatric Rheumatology

Figure 1

From: Dramatic pain relief and resolution of bone inflammation following pamidronate in 9 pediatric patients with persistent chronic recurrent multifocal osteomyelitis (CRMO)

Figure 1

Imaging data of sacral involvement by CRMO in patient 2, a 16-year-old boy. (A) Pre-treatment imaging: Coronal STIR MRI images reveal increased T2 signal in the ilium adjacent to the right sacroilial joint (SIJ), consistent with inflammation. (B) Imaging 2 months after initiation of pamidronate: Abnormal signal on coronal STIR has resolved. (C) Imaging at clinical relapse: Coronal STIR MRI image reveals increased T2 signal in the ilium adjacent to the left SIJ, consistent with inflammation. The previously affected right ilium demonstrates no abnormal signal. (D): Imaging 2 months post 1 day pamidronate retreatment: Previously demonstrated abnormal signal on coronal STIR is no longer seen.

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Pediatric Rheumatology

ISSN: 1546-0096