Skip to main content

Table 1 Comparison between our protocol and the ones published by Glorieux and Arikoski

From: Treatment of osteogenesis imperfecta with intravenous pamidronate in pediatric patients: comparison between a single-day infusion twice a year protocol with other regimens described in the literature

  HSJD Glorieux [1] Arikoski [2]
Patients 20 30 12
Dose (mg/Kg/year) 2.4(0.3) 6.8(1.1) 12
Periodicity of infusions (m) 6 3–4 3
Basal z-score -4.3(2) -5.3(1.2) *
Final z-score -3.38(2.4) ** -3.4(1.5) *
Years of treatment 3** 2.1(range 1.3–5) 1
Mean annual increase in: z-score BMD 0.49 (0.1) 21.1 (5.1) 0.95 41.9 (29) * 63.5(37.3)
  1. Mean(SD). m: months. *Data not available. ** For comparability with the other series only the results of the first 3 years are shown.