Table 1 Delphi 2 Responses in order of descending number of votes
PROBLEM | TREATMENT | VOTES |
|---|---|---|
Systemic onset juvenile rheumatoid arthritis | Anti-IL-6 receptor antibody | 62 |
Uveitis (juvenile rheumatoid arthritis, sarcoid, or idiopathic) unresponsive to methotrexate | Infliximab | 50 |
Pediatric systemic lupus erythematosus | Mycophenolate mofetil | 48 |
Thrombocytopenia unresponsive to standard therapy in systemic lupus erythematosus | Rituximab | 47 |
Juvenile dermatomyositis unresponsive to prednisone and disease-modifying anti-rheumatic drugs | Enbrel | 43 |
Systemic onset juvenile rheumatoid arthritis | Thalidomide | 43 |
Systemic onset juvenile rheumatoid arthritis | Anakinra | 36 |
Localized scleroderma | Combination: steroids and methotrexate | 35 |
Juvenile dermatomyositis unresponsive to prednisone and disease-modifying anti-rheumatic drugs | Infliximab | 29 |
Rash of juvenile dermatomyositis | Topical tacrolimus | 27 |
Systemic lupus erythematosus proliferative nephritis unresponsive to pulse cyclophosphamide and mycophenolate mofetil | Combination: pulse cyclophosphamide and mycophenolate mofetil | 25 |
Chronic Recurrent Multifocal Osteomyelitis that is not controlled by non-steroid anti-inflammatory drugs and/or that requires corticosteroids | Bisphosphonates | 24 |
Localized scleroderma | Methotrexate orally | 20 |
Linear scleroderma refractory to oral or subcutaneous methotrexate treatment | Oral mycophenolate mofetil treatment | 19 |
Henoch Scholein Purpura | Glucocorticoid treatment | 18 |
Osteoporosis | Alendronate and other possibilities | 18 |
Pauciarticular juvenile rheumatoid arthritis | Intraarticular steroids | 17 |
Systemic onset juvenile rheumatoid arthritis | Combination:TNF blockers and thalidomide | 17 |
Behcet's | Infliximab | 16 |
Early polyarticular juvenile rheumatoid arthritis | CTLA4-1g | 16 |
Macrophage activation syndrome | Combination: cyclosporin + corticosteroids | 15 |
Sarcoid arthritis | Enbrel | 15 |
Severe systemic lupus erythematosus – cyclophosphamide dependent or resistant | Intravenous fludarabine | 15 |
Rash of systemic lupus erythematosus | Topical tacrolimus | 14 |
Acute rheumatic fever | Naproxen | 13 |
Henoch Scholein Purpura with abdominal pain | Glucocorticoid treatment | 13 |
Juvenile rheumatoid arthritis-temporomandibular joint arthritis | Corticosteroid joint injections | 13 |
Systemic onset juvenile rheumatoid arthritis | Oral intravenous immunoglobulin as adjuvant therapy | 10 |
Familial Mediterranean fever not responsive to colchicine | Anakinra | 8 |
Refractory iritis in juvenile rheumatoid arthritis | Cyclosporin | 8 |
Osteoporosis | Vitamin D – the various preparations | 7 |
Raynaud's 10 and 20 | Biofeedback | 7 |
Familial Mediterranean fever | Anti-Interleukin 1 | 5 |
Systemic onset juvenile rheumatoid arthritis | Combination: hydroxychloroquine and standard therapy | 2 |
Systemic onset juvenile rheumatoid arthritis | Combination: thalidomide and cyclosporin | 2 |