Table 1 Characteristics of our patients with Takayasu arteritis.
Patient 1 | Patient 2 | Patient 3 | Patient 4 | |
|---|---|---|---|---|
Age at diagnosis (years) | 12 | 11 | 8 | 15 |
Gender (M, male; F, female) | F | M | F | M |
Ethnicity | Caucasian | Asian | Caucasian | Caucasian |
Clinical presentation | -pain left arm | -hypertension | - hypertension | -acute chest pain |
-absent radial and brachial pulse, weak left carotid pulse | -abdominal pain | |||
Laboratory findings at disease onset: | ||||
-ESR (mm/hr) | 80 | 125 | 100 | 80 |
-CRP (mg/l) | 60 | 80 | 134 | 60 |
-Hb (g/l) | 100 | 79 | 92 | 110 |
-platelets (G/l) | 400 | 738 | 487 | 745 |
Treatment (initial dose): | ||||
-prednisone (mg/kg/day) | 2 | 2 | 2 | 1.5 |
-methotrexate (mg/m2/wk) | 10 | 0 | 10 | 10 |
-MMF (mg bid) | 0 | 250 | 0 | 0 |
Surgical intervention | none | Bypass brachiocephalic trunk | Bypass abdominal aorta | None |
Follow up (years) | 10 | 3 | 9 | 3 |
Outcome and treatment at last visit | -Clinical remission | - Clinical remission | - Clinical remission | - Clinical remission |
-prednisone 5 mg/d | -prednisone 7.5 mg/d MMF 750 mg bid | -aspirin 100 mg/d | -prednisone 7.5 mg/d |