How safe it is to treat pregnant FMF patients with Anakinra?

Table 1 pregnancy-related features

Case	Maternal Age	Anakinra Relation to pregnancy	USGs	Weeks at delivery or currrent gestational age	Gender of the baby/fetus	Mode of the delivery	1^stminute APGAR	Follow-up duration after birth (months)	Complications after birth
1	33	started at 21st GW and used continiously until birth	normal	Birth at 36th GW	boy	C/S	8	32	No
2	28	started at 12th GW and used until birth	normal	Birth at 40th GW	girl	vaginal	10	20	No
3	31	started at 12th GW and used until birth	normal	Birth at 38th GW	boy	C/S	6	2	Methicillin-Sensitive Staphylococcus Aureus incision-site infection (treated with Tygecycline) in mother
4	24	started at 15th GW and used until birth	normal	Birth at 38th GW	boy	Vaginal	8	2	Low thrombocyte count in the baby at birth (23,000/mm3); resolved after 3 infusions of IVIG (269,000/mm3)
5	33	started at 16th GW, still using	normal	At 20th GW	Expecting 2 girls

ISSN: 1546-0096