Table 1 Correlation of laboratory parameters of disease activity with IFN-g, CXCL9, CXCL10, CXCL11 and IL-6 in patients with MAS and in patients with active sJIA
Macrophage Activation Syndrome | IFNg | CXCL9 | CXCL10 | CXCL11 | IL-6 | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
r* | p | r* | p | r* | p | r* | p | r* | p | ||
Ferritin | 8000 (3158 - 13174) [1] | 0.57 | 0.014 | 0.49 | 0.041 | 0.66 | 0.002 | 0.62 | 0.023 | 0.17 | >0.1 |
N | 6.9 (3.4 - 13.9) [1] | -0.64 | 0.005 | -0.61 | 0.010 | -0.37 | >0.1 | -0.08 | >0.1 | 0.09 | >0.1 |
PLT | 197 (114 - 392) [1] | -0.53 | 0.017 | -0.52 | 0.022 | -0.58 | 0.008 | -0.22 | >0.1 | -0.02 | >0.1 |
ALT | 46 (18 - 164) [1] | 0.49 | 0.045 | 0.49 | 0.044 | 0.51 | 0.038 | 0.06 | >0.1 | -0.44 | 0.080 |
LDH | 1152 (722 - 2135) [1] | 0.45 | 0.095 | 0.62 | 0.013 | 0.64 | 0.001 | 0.64 | 0.048 | 0.08 | >0.1 |
Sistemic Juvenile Idiopathic Arthritis | r* | p | r* | p | r* | p | r* | P | r* | p | |
Ferritin | 214 (37 - 1669) [1] | -0.27 | >0.1 | 0.28 | >0.1 | 0.27 | >0.1 | 0.29 | >0.1 | -0.12 | >0.1 |
N | 8.4 (5.2 - 14.5) [1] | 0.30 | >0.1 | 0.40 | 0.061 | 0.32 | >0.1 | 0.40 | 0.067 | 0.28 | >0.1 |
PLT | 444 (353 - 544) [1] | 0.21 | >0.1 | -0.14 | >0.1 | -0.13 | >0.1 | 0.27 | >0.1 | 0.35 | 0.064 |
ALT | 16 (11 - 24) [1] | 0.29 | >0.1 | 0.42 | 0.049 | 0.50 | 0.011 | 0.44 | 0.039 | 0.04 | >0.1 |
LDH | 506 (455 - 851) [1] | 0.07 | >0.1 | 0.49 | >0.1 | 0 | >0.1 | 0.26 | >0.1 | 0 | >0.1 |