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Table 1

From: Long-term outcomes in childhood-onset systemic lupus erythematosus: preliminary results of the CHILL-NL study

Characteristic

Frequency (median + range)

Age at diagnosis

13 years (9 – 18)

Disease duration

15 years (4 – 36)

SLEDAI-score

4 (0 – 9)

SDI

1 (0 – 7)

Cumulative organ involvement

 

Skin

90%

Muskuloskeletal

83%

Haematological

83%

Renal

65%

Central nervous system

48%

Pulmonary

46%

Cardiovascular

36%

Abdominal

19%

Peripheral nervous system

10%

(Vertebral) fractures

23%

Severe infections (hospitalization necessary)

32%

Medication use

Current

Ever

Prednisone

52%

100%

Azathioprine

25%

64%

Cyclophosphamide

0%

36%

Hydroxychloroquine

63%

85%

Rituximab

0%

11%

MMF

27%

46%

Family history

1 st degree

2 nd degree

SLE

14%

0%

other auto-immune diseases

55%

57%