Characteristic | Frequency (median + range) | |
---|---|---|
Age at diagnosis | 13 years (9 – 18) | |
Disease duration | 15 years (4 – 36) | |
SLEDAI-score | 4 (0 – 9) | |
SDI | 1 (0 – 7) | |
Cumulative organ involvement | Â | |
Skin | 90% | |
Muskuloskeletal | 83% | |
Haematological | 83% | |
Renal | 65% | |
Central nervous system | 48% | |
Pulmonary | 46% | |
Cardiovascular | 36% | |
Abdominal | 19% | |
Peripheral nervous system | 10% | |
(Vertebral) fractures | 23% | |
Severe infections (hospitalization necessary) | 32% | |
Medication use | Current | Ever |
Prednisone | 52% | 100% |
Azathioprine | 25% | 64% |
Cyclophosphamide | 0% | 36% |
Hydroxychloroquine | 63% | 85% |
Rituximab | 0% | 11% |
MMF | 27% | 46% |
Family history | 1 st degree | 2 nd degree |
SLE | 14% | 0% |
other auto-immune diseases | 55% | 57% |