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Table 1

From: Factors associated with choice of first biologic among children with juvenile idiopathic arthritis: a combined analysis from two UK paediatric biologic registers

Biologic start post 01/01/2010, unless specified.

*All values median(IQR) or n(%)

Etanercept

[N=165]

Adalimumab

[N=45]

Infliximab

[N=29]

Tocilizumab

[N=32]

Anakinra

[N=15]

Pre-2010 Etanercept

[N=582]

Female

109 (67%)

30 (67%)

17 (59%)

14 (44%)

11 (73%)

384 (66%)

Age, years

11 (8, 14)

10 (6, 14)

8 (5, 10)

8 (4, 11)

3 (2, 13)

11 (8, 14)

Disease duration, years

2 (1, 5)

4 (2, 6)

3 (2, 6)

1 (1, 2)

0 (0, 1)

4 (2, 7)

ILAR Category

      

Systemic arthritis

5 (3%)

1 (2%)

1 (3%)

28 (88%)

15

70 (12%)

Oligoarthritis

39 (24%)

24 (53%)

16 (55%)

0

(100%)

117 (20%)

Polyarthritis

83 (50%)

9 (20%)

9 (31%)

3 (9%)

0

253 (43%)

Enthesitis Related Arthritis

10 (6%)

5 (11%)

2 (7%)

0

0

50 (9%)

Psoriatic arthritis

10 (6%)

5 (11%)

1 (3%)

0

0

44 (8%)

Other

18 (11%)

1 (2%)

0

1 (3%)

0

48 (8%)

     

0

 

Concomitant MTX

77 (47%)

31 (69%)

26 (90%)

28 (88%)

12 (80%)

322 (55%)

Concomitant corticosteroids

15 (9%)

7 (16%)

5 (17%)

23 (72%)

7 (47%)

146 (25%)

Ever had uveitis

7 (5%)

31 (70%)

21 (72%)

0

0

54 (11%)

CHAQ [0-3]

1 (0, 2)

1 (0, 1)

0 (0, 1)

1 (0, 2)

2 (1, 2)

1 (0, 2)

JADAS-71

13 (8, 21)

10 (7, 17)

6 (3, 12)

19 (1, 22)

23 (7, 30)

16 (9, 23)