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Table Inactive Disease - Multivariate logistic regression analysis on 12-week data

From: Predictors of response in patients with active systemic JIA (SJIA) receiving canakinumab: an exploratory analysis of pooled 12-week data

Variable*, Odds Ratio (95% CI) Day 15 Day 29 Day 57 Day 85
CRP at Day 15 (elevated vs normal) 0.20 (0.07, 0.55) 0.14 (0.04, 0.41) 0.26 (0.10, 0.66) 0.31 (0.12, 0.82)
Number of active joints (11-≤20 vs. ≤10) 0.22 (0.03, 1.66) 0.55 (0.09, 3.41) 0.17 (0.031, 0.97) 0.37 (0.06, 2.10)
Number of active joints (≤10 vs. >20) 2.56 (0.12, 55.39) 1.53 (0.06, 37.44) 16.10 (1.00, 258.12) 25.41 (1.60, 404.61)
Prior NSAID treatment (no vs. yes) 2.01 (0.71, 5.71) 9.33 (2.44, 35.68) 3.10 (1.03, 9.31) 5.31 (1.66, 17.05)
Steroid Level (0 vs. >0.4 mg/kg/day) 5.48 (0.97, 31.01) 8.89 (1.26, 62.64) 2.98 (0.51, 17.46) 11.16 (1.72, 72.34)
Steroid Level (>0.4 vs. >0-≤0.4 mg/kg/day) 0.32 (0.08, 1.29) 0.41 (0.09, 1.82) 0.81 (0.25, 2.60) 0.13 (0.03, 0.57)
Prior MTX treatment (no vs. yes) 1.94 (0.75, 5.00) 2.78 (0.93, 8.33) 2.79 (1.04, 7.51) 1.77 (0.65, 4.83)
Prior anti-TNFs treatment (no vs. yes) 1.83 (0.52, 6.49) 3.62 (0.77, 17.00) 2.01 (0.63, 6.38) 3.64 (1.04, 12.77)
  1. Values in bold are significant; *Significant in at least one time point