Table Inactive Disease - Multivariate logistic regression analysis on 12-week data

Variable*, Odds Ratio (95% CI)

Day 15

Day 29

Day 57

Day 85

CRP at Day 15 (elevated vs normal)

0.20 (0.07, 0.55)

0.14 (0.04, 0.41)

0.26 (0.10, 0.66)

0.31 (0.12, 0.82)

Number of active joints (11-≤20 vs. ≤10)

0.22 (0.03, 1.66)

0.55 (0.09, 3.41)

0.17 (0.031, 0.97)

0.37 (0.06, 2.10)

Number of active joints (≤10 vs. >20)

2.56 (0.12, 55.39)

1.53 (0.06, 37.44)

16.10 (1.00, 258.12)

25.41 (1.60, 404.61)

Prior NSAID treatment (no vs. yes)

2.01 (0.71, 5.71)

9.33 (2.44, 35.68)

3.10 (1.03, 9.31)

5.31 (1.66, 17.05)

Steroid Level (0 vs. >0.4 mg/kg/day)

5.48 (0.97, 31.01)

8.89 (1.26, 62.64)

2.98 (0.51, 17.46)

11.16 (1.72, 72.34)

Steroid Level (>0.4 vs. >0-≤0.4 mg/kg/day)

0.32 (0.08, 1.29)

0.41 (0.09, 1.82)

0.81 (0.25, 2.60)

0.13 (0.03, 0.57)

Prior MTX treatment (no vs. yes)

1.94 (0.75, 5.00)

2.78 (0.93, 8.33)

2.79 (1.04, 7.51)

1.77 (0.65, 4.83)

Prior anti-TNFs treatment (no vs. yes)

1.83 (0.52, 6.49)

3.62 (0.77, 17.00)

2.01 (0.63, 6.38)

3.64 (1.04, 12.77)