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Table 1 Main clinical, epidemiological, laboratory and instrumental results collected from mothers with autoimmune diseases and their children

From: Bone status of children born from mothers with autoimmune diseases treated during pregnancy with prednisone and/or low molecular weight heparin

Mother

Pregnancy

Diagnosis in mothers

Autoantibody positivity in mothers

Treatment during pregnancy

Concomitant medications

Gestational age (weeks + days)

Post-partum complications

Child age at clinic visit (years and months)

BMI at visit

QUS (percentile)

1

a

PAPS

none

Enoxiparin 2000 UI bid.

Aspirin

38

None

7 yrs 6 mo

14.9

97

1

b

PAPS

none

Enoxiparin 2000 UI bid.

Aspirin

36

None

9 yrs

17.3

75

2

a

Sjögren

ANA

Enoxiparin 2000 UI bid.

None

40

None

8 yrs 9 mo

15.9

75

3

a

SLE

ANA, ENA

Enoxiparin 2000 UI bid.

Aspirin

30 + 4

None

5 yrs 1 mo

16.9

75-90

3

b

SLE

ANA, ENA

Enoxiparin 2000 UI bid.

Aspirin

36 + 5

None

2 yrs

16.1

< 3

4

a

UCTD

ANA, LAC

Enoxiparin 2000 UI bid.

Aspirin

39 + 4

None

6 yrs 2 mo

16.8

97

5

a

PAPS

ANA, ENA, LAC, aCL IgM

Nadroparin 3800 UI daily

Aspirin

39 + 4

None

5 yrs 3 mo

15.4

25

6

a

Systemic Sclerosis

ANA, aCL IgM

Nadroparin3800 UI daily

None

38 + 4

None

6 yrs 4 mo

16.1

< 3

6

b

Systemic Sclerosis

ANA, aCL IgM

Nadroparin3800 UI daily

None

38

None

9 yrs 4 mo

19.5

< 25

7

a

SLE

ANA, ENA, LAC, aCL IgM, aCL IgG

Enoxiparin 4000 UI daily

Aspirin

40

None

3 yrs 9 mo

17.2

< 3

8

a

SLE

ANA, aCL IgM

Methylprednisolone 4 mg daily

None

40

None

2 yrs 3 mo

17.1

> 97

9

a

MCTD

ANA, ENA

Methylprednisolone 4 mg daily

None

40

None

6 yrs 9 mo

15.8

75

10

a

Granulomatosis with polyangitis

ANA, ANCA

Prednisone 15 mg daily

IVIG

40

None

7 yrs 9 mo

16.5

25

10

b

Granulomatosis with polyangitis

ANA, ANCA

Prednisone 15 mg daily

IVIG

40

None

9 yrs

24

75

11

a

SLE

ANA, anti-DNA, aCL IgG

Prednisone 25 mg daily

IVIG

36

Post-partum bleeding

8 yrs 3 mo

14.4

50

12

b

SLE

ANA, ENA, anti-DNA, aCL IgG, aCL IgM

Prednisone 25 mg daily

Aspirin

37 + 1

None

1 yrs 4 mo

16.4

25

13

a

SLE

ANA

Prednisone 25 mg daily

None

36 + 4

None

9 yrs 3 mo

16.7

50

13

b

SLE

ANA

Prednisone 25 mg daily

None

39

None

10 yrs 7 mo

18.9

75

14

a

SLE

ANA

Prednisone 5 mg daily

Aspirin

40

None

5 yrs 5 mo

15.4

50

15

b

Sjögren

ANA, ENA

Prednisone 5 mg daily

None

40

None

2 yrs 4 mo

12.4

50

16

a

RA

None

Prednisone 5 mg daily

None

39

None

12 yrs

14.5

25

16

b

RA

None

Prednisone 5 mg daily

None

40

None

4 yrs 5 mo

14

75

17

a

SLE

ANA, ENA, anti-DNA

Prednisone 5 mg daily

Aspirin

40

None

6 yrs 7 mo

12.2

25

17

b

SLE

ANA, ENA, anti-DNA

Prednisone 5 mg daily

Aspirin

40

None

3 yrs 9 mo

14

50

18

a

UCTD

ANA

Methylprednisolone 5 mg daily

None

39 + 5

None

1 yrs

16.2

< 3

19

b

SLE

ANA

Methylprednisolone 4 mg daily

Aspirin

40

None

6 yrs 4 mo

21.2

50

20

a

SLE

ANA, anti-DNA

Enoxiparin 4000 UI daily + Prednisolone 4 mg daily

None

40

None

10 yrs 9 mo

25.7

75

21

a

PAPS

ACL IgG, anti-β2GPI

Nadroparin 3800 UI daily + Prednisone 5 mg daily

None

34

Mitralic insufficiency

5 yrs 10 mo

15

25

21

b

PAPS

ACL IgG, anti-β2GPI

Nadroparin3800 UI daily + Prednisone 5 mg daily

None

34

Thrombocytopenia

9 yrs 7 mo

20.1

25-50

22

a

SLE

ANA, ENA, anti-DNA

Nadroparin2850 UI daily + Methylprednisolone 4 mg daily

None

38

None

11 yrs 3 mo

17.5

97

22

b

SLE

ANA, ENA, anti-DNA

Nadroparin2850 UI daily + Methylprednisolone 4 mg daily

None

36 + 5

None

5 yrs 5 mo

15.8

< 3

23

a

MCTD

ENA, aCL IgG

Enoxiparin 4000 UI daily + Prednisone 5 mg daily

None

37 + 1

None

9 mo

17.5

25

24

a

SLE

ANA, anti-DNA, aCL IgG, anti-β2GPI

Enoxiparin 4000 UI daily + Prednisone 10 mg daily

IVIG + Aspirin

40

None

10 yrs

25

< 3

24

b

SLE

ANA, anti-DNA, aCL IgG, anti-β2GPI

Enoxiparin 4000 UI daily + Prednisone 10 mg daily

IVIG + Aspirin

38

None

4 yrs 7 mo

15.4

< 3

25

a

SLE

ANA

Enoxiparin 4000 UI daily + Prednisone 25 mg daily

IVIG

40

None

1 yrs 5 mo

15.3

< 3

26

a

UCTD

ENA, aCL IgM

Enoxiparin 4000 UI daily + Prednisone 5 mg daily

None

36

None

10 yrs 9 mo

16.6

25

27

a

UCTD

ENA

Enoxiparin 4000 UI daily + Prednisone 5 mg daily

Aspirin

40

None

9 mo

16

97

28

a

UCTD

ENA, anti-β2GPI

Enoxiparin 4000 UI daily + Prednisone 5 mg daily

Aspirin

37

None

2 yrs 3 mo

19.1

97

29

a

SLE

ANA, ENA, LAC, anti-DNA

Enoxiparin 4000 UI daily + Prednisone 5 mg daily

None

40

None

5 yrs 11 mo

21.8

25

30

a

SLE

ANA

Nadroparin2850 UI daily + Prednisolone 8 mg daily

None

34

Hepatogestosis

11 mo

15.6

25

31

a

SLE

ANA

Nadroparin2850 UI daily + Prednisolone 8 mg daily

None

25 + 1

Hepatogestosis

5 yrs

13.8

25

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Pediatric Rheumatology

ISSN: 1546-0096