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Table 1 Main clinical, epidemiological, laboratory and instrumental results collected from mothers with autoimmune diseases and their children

From: Bone status of children born from mothers with autoimmune diseases treated during pregnancy with prednisone and/or low molecular weight heparin

Mother Pregnancy Diagnosis in mothers Autoantibody positivity in mothers Treatment during pregnancy Concomitant medications Gestational age (weeks + days) Post-partum complications Child age at clinic visit (years and months) BMI at visit QUS (percentile)
1 a PAPS none Enoxiparin 2000 UI bid. Aspirin 38 None 7 yrs 6 mo 14.9 97
1 b PAPS none Enoxiparin 2000 UI bid. Aspirin 36 None 9 yrs 17.3 75
2 a Sjögren ANA Enoxiparin 2000 UI bid. None 40 None 8 yrs 9 mo 15.9 75
3 a SLE ANA, ENA Enoxiparin 2000 UI bid. Aspirin 30 + 4 None 5 yrs 1 mo 16.9 75-90
3 b SLE ANA, ENA Enoxiparin 2000 UI bid. Aspirin 36 + 5 None 2 yrs 16.1 < 3
4 a UCTD ANA, LAC Enoxiparin 2000 UI bid. Aspirin 39 + 4 None 6 yrs 2 mo 16.8 97
5 a PAPS ANA, ENA, LAC, aCL IgM Nadroparin 3800 UI daily Aspirin 39 + 4 None 5 yrs 3 mo 15.4 25
6 a Systemic Sclerosis ANA, aCL IgM Nadroparin3800 UI daily None 38 + 4 None 6 yrs 4 mo 16.1 < 3
6 b Systemic Sclerosis ANA, aCL IgM Nadroparin3800 UI daily None 38 None 9 yrs 4 mo 19.5 < 25
7 a SLE ANA, ENA, LAC, aCL IgM, aCL IgG Enoxiparin 4000 UI daily Aspirin 40 None 3 yrs 9 mo 17.2 < 3
8 a SLE ANA, aCL IgM Methylprednisolone 4 mg daily None 40 None 2 yrs 3 mo 17.1 > 97
9 a MCTD ANA, ENA Methylprednisolone 4 mg daily None 40 None 6 yrs 9 mo 15.8 75
10 a Granulomatosis with polyangitis ANA, ANCA Prednisone 15 mg daily IVIG 40 None 7 yrs 9 mo 16.5 25
10 b Granulomatosis with polyangitis ANA, ANCA Prednisone 15 mg daily IVIG 40 None 9 yrs 24 75
11 a SLE ANA, anti-DNA, aCL IgG Prednisone 25 mg daily IVIG 36 Post-partum bleeding 8 yrs 3 mo 14.4 50
12 b SLE ANA, ENA, anti-DNA, aCL IgG, aCL IgM Prednisone 25 mg daily Aspirin 37 + 1 None 1 yrs 4 mo 16.4 25
13 a SLE ANA Prednisone 25 mg daily None 36 + 4 None 9 yrs 3 mo 16.7 50
13 b SLE ANA Prednisone 25 mg daily None 39 None 10 yrs 7 mo 18.9 75
14 a SLE ANA Prednisone 5 mg daily Aspirin 40 None 5 yrs 5 mo 15.4 50
15 b Sjögren ANA, ENA Prednisone 5 mg daily None 40 None 2 yrs 4 mo 12.4 50
16 a RA None Prednisone 5 mg daily None 39 None 12 yrs 14.5 25
16 b RA None Prednisone 5 mg daily None 40 None 4 yrs 5 mo 14 75
17 a SLE ANA, ENA, anti-DNA Prednisone 5 mg daily Aspirin 40 None 6 yrs 7 mo 12.2 25
17 b SLE ANA, ENA, anti-DNA Prednisone 5 mg daily Aspirin 40 None 3 yrs 9 mo 14 50
18 a UCTD ANA Methylprednisolone 5 mg daily None 39 + 5 None 1 yrs 16.2 < 3
19 b SLE ANA Methylprednisolone 4 mg daily Aspirin 40 None 6 yrs 4 mo 21.2 50
20 a SLE ANA, anti-DNA Enoxiparin 4000 UI daily + Prednisolone 4 mg daily None 40 None 10 yrs 9 mo 25.7 75
21 a PAPS ACL IgG, anti-β2GPI Nadroparin 3800 UI daily + Prednisone 5 mg daily None 34 Mitralic insufficiency 5 yrs 10 mo 15 25
21 b PAPS ACL IgG, anti-β2GPI Nadroparin3800 UI daily + Prednisone 5 mg daily None 34 Thrombocytopenia 9 yrs 7 mo 20.1 25-50
22 a SLE ANA, ENA, anti-DNA Nadroparin2850 UI daily + Methylprednisolone 4 mg daily None 38 None 11 yrs 3 mo 17.5 97
22 b SLE ANA, ENA, anti-DNA Nadroparin2850 UI daily + Methylprednisolone 4 mg daily None 36 + 5 None 5 yrs 5 mo 15.8 < 3
23 a MCTD ENA, aCL IgG Enoxiparin 4000 UI daily + Prednisone 5 mg daily None 37 + 1 None 9 mo 17.5 25
24 a SLE ANA, anti-DNA, aCL IgG, anti-β2GPI Enoxiparin 4000 UI daily + Prednisone 10 mg daily IVIG + Aspirin 40 None 10 yrs 25 < 3
24 b SLE ANA, anti-DNA, aCL IgG, anti-β2GPI Enoxiparin 4000 UI daily + Prednisone 10 mg daily IVIG + Aspirin 38 None 4 yrs 7 mo 15.4 < 3
25 a SLE ANA Enoxiparin 4000 UI daily + Prednisone 25 mg daily IVIG 40 None 1 yrs 5 mo 15.3 < 3
26 a UCTD ENA, aCL IgM Enoxiparin 4000 UI daily + Prednisone 5 mg daily None 36 None 10 yrs 9 mo 16.6 25
27 a UCTD ENA Enoxiparin 4000 UI daily + Prednisone 5 mg daily Aspirin 40 None 9 mo 16 97
28 a UCTD ENA, anti-β2GPI Enoxiparin 4000 UI daily + Prednisone 5 mg daily Aspirin 37 None 2 yrs 3 mo 19.1 97
29 a SLE ANA, ENA, LAC, anti-DNA Enoxiparin 4000 UI daily + Prednisone 5 mg daily None 40 None 5 yrs 11 mo 21.8 25
30 a SLE ANA Nadroparin2850 UI daily + Prednisolone 8 mg daily None 34 Hepatogestosis 11 mo 15.6 25
31 a SLE ANA Nadroparin2850 UI daily + Prednisolone 8 mg daily None 25 + 1 Hepatogestosis 5 yrs 13.8 25