Figure 5From: Immunity against Mycobacterium tuberculosis and the risk of biologic anti-TNF-α reagentsKey functions of the tumor necrosis factor (TNF)-α cytokine in tuberculosis. (A) TNF-α recruits neutrophils, macrophages and T-lymphocytes to the infection site; (B) The cytokine maintains granuloma formation in tuberculosis; (C) The autocrinal TNF-α is also produced and induces apoptosis of TB-infected cells.Back to article page