The pro-inflammatory potential of T cells in juvenile-onset systemic lupus erythematosus

Table 1 Juvenile-onset SLE patient data

Demographics	Juvenile-onset SLE patients (n = 30)
Number (%) female	22 (73%)
Ethnicity, number
White British	22
White other	1
Asian	7
Age at sampling, mean (range) years	12.4 (3.4 – 17.9)
Disease duration, mean (range) years	2.9 (0.01 – 10.2)
Biomarker/disease activity parameter, mean (range)
ESR, mm/hour (normal 2 – 8 mm/hour)	9.3 (<1 – 60)
CRP, mg/litre (normal 0 – 8 mg/litre)	6.8 (<4 – 78)
C3, gm/litre (normal 1.1 – 1.9)	1.03 (0.4 – 1.37)
C4, gm/litre (normal 0.19 – 0.56)	0.20 (0.08 – 0.46)
Anti-dsDNA titre, IU/ml (normal <7)	7.6 (0 – 96)
C-HAQ score, 0–3, mean (range)	0.32 (0 – 1.5)
Physician’s global assessment of disease activity by VAS, mean (range) mm	20 (0 – 75)
SLEDAI score, mean (range)	4.4 (0 – 17)
BILAG-2004	4.4 (0 – 17)
Number with grade A or grade B	9
Score, mean (range)	2.03 (0 – 8)
Current medications number of patients
Hydroxychloroquine	23
Methotrexate	3
Azathioprine	7
Mycophenolate mofetil	12
Prednisolone	13
Prednisolone dosage, mean (range) mg/day	12.2 (1 – 40)
Rituximab	4

Data on demographics, biomarker parameters, pBILAG2004 disease activity scores, and current medications in patients with juvenile-onset SLE.
BILAG = British Isles Lupus Assessment Group; SLE = systemic lupus erythematosus; ESR = erythrocyte sedimentation rate; CRP = C-reactive protein; anti-dsDNA = anti–double-stranded DNA; C-HAQ = Childhood Health Assessment Questionnaire; VAS = visual analog scale (0–100-mm).

ISSN: 1546-0096