Skip to main content

Table 3 Absolute QST values at control site (thenar eminence) in children with JIA according to joint inflammation status a

From: Pain hypersensitivity in juvenile idiopathic arthritis: a quantitative sensory testing study

  Upper extremity Lower extremity  
QST parameter Active joint (n = 11) Inactive joint (n = 20) Active joint (n = 12) Inactive joint (n = 17) p-value b
Innocuous stimulus
MDT (g) 0.04 (0.03-0.08) 0.04 (0.02-0.05) 0.04 (0.02-0.05) 0.05 (0.04-0.09) 0.08
VDT (μm/sec) 0.58 (0.42-1.20) 0.69 (0.59-1.03) 0.64 (0.50-0.81) 0.80 (0.63-0.91) 0.35
CDT (°C) 30.4 (29.5-30.8) 30.2 (29.7-30.7) 29.9 (29.2-30.5) 30.2 (27.5-30.6) 0.60
WDT (°C) 34.8 (33.8-36.0) 34.6 (34.2-35.2) 34.8 (34.2-36.5) 34.9 (33.7-35.5) 0.95
Noxious stimulus
MPT (g) 0.8 (0.4-1.4) 1.0 (0.4-2.5) 1.2 (0.8-3.7) 1.3 (0.6-4.5) 0.46
PPT (N) 6.1 (4.5-15.0) 10.7 (8.4-16.3) 11.3 (5.8-16.9) 9.7 (7.4-15.2) 0.58
CPT (°C) 29.1 (25.0-30.6) 25.7 (14.3-29.0) 21.1 (15.5-25.4) 26.6 (22.0-28.9) 0.03 c
HPT (°C) 37.2 (35.7-40.3) 37.8 (35.4-43.0) 41.1 (38.6-45.5) 37.5 (35.9-43.2) 0.17
  1. CDT- Cold Detection Threshold, CPT, Cold Pain Threshold; HPT, Heat Pain Threshold; IQR- Inter-Quartile Range; MDT- Mechanical Detection Threshold; MPT- Mechanical Pain Threshold; PPT, Pressure Detection Threshold; VDT- Vibration Detection Threshold; WDT- Warm Detection Threshold.
  2. a.All values given as median (IQR) unless otherwise stated. Eight children with JIA were taking daily NSAIDs at the time of study. b.p-values indicate differences in sensory threshold between all four groups using Kruskal-Wallis testing. Boldface highlights significant differences. c.Significant differences for CPT found between JIA patients with active arthritis in the upper extremity vs lower extremity after Dunn’s correction for multiple comparisons; no other comparisons were different.