Skip to main content

Table 3 Absolute QST values at control site (thenar eminence) in children with JIA according to joint inflammation status a

From: Pain hypersensitivity in juvenile idiopathic arthritis: a quantitative sensory testing study

 

Upper extremity

Lower extremity

 

QST parameter

Active joint (n = 11)

Inactive joint (n = 20)

Active joint (n = 12)

Inactive joint (n = 17)

p-value b

Innocuous stimulus

MDT (g)

0.04

(0.03-0.08)

0.04

(0.02-0.05)

0.04

(0.02-0.05)

0.05

(0.04-0.09)

0.08

VDT (μm/sec)

0.58

(0.42-1.20)

0.69

(0.59-1.03)

0.64

(0.50-0.81)

0.80

(0.63-0.91)

0.35

CDT (°C)

30.4

(29.5-30.8)

30.2

(29.7-30.7)

29.9

(29.2-30.5)

30.2

(27.5-30.6)

0.60

WDT (°C)

34.8

(33.8-36.0)

34.6

(34.2-35.2)

34.8

(34.2-36.5)

34.9

(33.7-35.5)

0.95

Noxious stimulus

MPT (g)

0.8

(0.4-1.4)

1.0

(0.4-2.5)

1.2

(0.8-3.7)

1.3

(0.6-4.5)

0.46

PPT (N)

6.1

(4.5-15.0)

10.7

(8.4-16.3)

11.3

(5.8-16.9)

9.7

(7.4-15.2)

0.58

CPT (°C)

29.1

(25.0-30.6)

25.7

(14.3-29.0)

21.1

(15.5-25.4)

26.6

(22.0-28.9)

0.03 c

HPT (°C)

37.2

(35.7-40.3)

37.8

(35.4-43.0)

41.1

(38.6-45.5)

37.5

(35.9-43.2)

0.17

  1. CDT- Cold Detection Threshold, CPT, Cold Pain Threshold; HPT, Heat Pain Threshold; IQR- Inter-Quartile Range; MDT- Mechanical Detection Threshold; MPT- Mechanical Pain Threshold; PPT, Pressure Detection Threshold; VDT- Vibration Detection Threshold; WDT- Warm Detection Threshold.
  2. a.All values given as median (IQR) unless otherwise stated. Eight children with JIA were taking daily NSAIDs at the time of study. b.p-values indicate differences in sensory threshold between all four groups using Kruskal-Wallis testing. Boldface highlights significant differences. c.Significant differences for CPT found between JIA patients with active arthritis in the upper extremity vs lower extremity after Dunn’s correction for multiple comparisons; no other comparisons were different.