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Table 1 Age, gender and clinical characteristics of children with JIA a

From: Pain hypersensitivity in juvenile idiopathic arthritis: a quantitative sensory testing study

  JIA patients  
  QST joint status  
Characteristics Total (n = 60) Active (n = 23) Inactive (n = 37) p-value b
Female patients, n (%) 44 (73%) 17 (74%) 27 (73%) 0.94c
Age at study visit, years 13.0 (9.6-15.5) 10.6 (9.4-15.0) 14.4 (9.7-15.9) 0.22
Duration of rheumatology clinic attendance, years, mean (SD) 5.8 (3.9) 4.9 (4.0) 6.4 (3.8) 0.17d
Markers of disease activity
Physician's global assessment of overall disease activitye 1.0 (0.0-2.0) 2.0 (1.0-3.0) 0.7 (0.0-1.1) <0.01
No. of active joints 1.0 (0.0-3.0) 3.0 (2.0-9.0) 0.0 (0.0-0.5) <0.001
Patient's pain assessmentf 0.0 (0.0-2.0) 2.0 (0.0-3.5) 0.0 (0.0-2.0) 0.21
Patient's global assessment of overall wellbeingg 1.0 (0.0-2.7) 1.2 (0.6-2.8) 0.0 (0.0-2.9) 0.10
C-HAQ scoreh 0.0 (0.0-0.13) 0.0 (0.0-0.25) 0.0 (0.0-0.0) 0.13
Erythrocyte sedimentation rate, mm/houri 8.0 (4.0-11.0) 8.5 (5.0-12.5) 8.0 (3.0-11.0) 0.37
C-reactive protein level, mg/Lj 0.1 (0.04-0.2) 0.1 (0.07-0.26) 0.1 (0.04-0.2) 0.77
Medications (n)
Methotrexate 33 (55%) 14 19  
Etanercept 16 (27%) 6 10  
Infliximab 6 (10%) 1 5  
Leflunomide 2 (3%) 0 2  
Sulfasalazine 1 (1.6%) 0 1  
  1. C-HAQ: Child Health Assessment Questionnaire; IQR- Inter-Quartile Range; QST- Quantitative Sensory Testing; SD, Standard deviation.
  2. a.All values given as median (IQR) unless otherwise stated. b.p-values indicate differences in JIA patients with active compared to clinically inactive joints. Mann–Whitney test used unless otherwise stated. Boldface highlights significant differences. c.Fisher’s Exact test. d.Unpaired Student’s t-test. e.Data available for 29 patients (Active, n = 7; Inactive, n = 22). f.Data available for 55 patients (Active, n = 21; Inactive, n = 34). g.Measured on a 100 mm visual analogue scale (0, best; 10, worst). Data available for 43 patients: Active, n = 17; Inactive, n = 26) h.Data available for 45 patients (Active, n = 17; Inactive, n = 28). i.Data available for 51 patients (Active, n = 20; Inactive, n = 31). j.Data available for 53 patients (Active, n = 21; Inactive, n = 32).