Figure 1

Noxious thresholds for pressure, cold and heat pain at thenar eminence. Pressure, and temperature change from baseline, where the sensation of (A) pressure, (B) cold and (C) heat pain were perceived are plotted for JIA patients (JIA, n = 58), and controls (EU, n = 151; US, n = 92). JIA patients were hypersensitive to all modalities. MPT is not included because we do not have comparison values from healthy controls. Individuals represented by single dots, Box and Whisker plot illustrates median, IQR and range. *p < 0.05; **p < 0.01; ***p < 0.001.