Treatment of juvenile idiopathic arthritis: a revolution in care

Table 1 JIA subtypes ^§

Feature	Oligoarticular	RF – polyarticular	RF + polyarticular	Systemic	ERA	Psoriatic
Peak age of onset	1 – 3 years	Dual peaks	Teenage	2 years	Teenage	Dual peaks
Sex	F > M	F > M	F > M	Equal	M > F	*F > M
ANA+	Majority	Majority	Rare	Rare	Rare	Majority of younger age
RF+	No	No	Yes	No	No	No
HLA-B27+	No	No	No	No	Majority	Majority of older age
Uveitis	Silent	Silent	Rare	Rare	Typically acute	Silent
Enthesitis	No	No	No	No	Yes	Older age
Dactylitis	Rare	No	No	No	Yes	Yes
Fevers	No	No	No	High-spiking	No	No

^§By definition, children with unclassified JIA meet criteria for none or for two or more of the categories listed in the table. *Among psoriatics with an older age of onset, the male: female ratio is close to 1, and the incidence of positive ANA is lower. Abbreviations: ERA – enthesitis related arthritis. Adapted from [2].

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