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Figure 1 | Pediatric Rheumatology

Figure 1

From: The involvement of the vasa vasorum in the development of vasculitis in animal model of Kawasaki disease

Figure 1

The four developmental stages in the murine model of Kawasaki disease like vasculitis based on the histopathological analysis. In hematoxylin and eosin (HE)-stained sections, there were some inflammatory cells visible in the adventitia one week after the CAWS injection (red arrows). Obvious infiltration of inflammatory cells was detected more than two weeks after the injections of the Candida albicans water-soluble fraction (CAWS) (red arrows). Three weeks after the injection, marked adventitial thickening was detected.In elastica van Gieson (EVG)-stained sections, the elastic fibers started to be destroyed more than two weeks after the injections of CAWS (yellow arrows). RCC: Right Coronary Cusp, LCC: Left Coronary Cusp, NCC: Non Coronary Cusp, CA: Coronary Artery.

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Pediatric Rheumatology

ISSN: 1546-0096