Table 1
From: PReS-FINAL-2083: The rate of malignancy in iranian children with joint manifestations
Period of Study | Study Center | Malignant cases with MS symptoms/total patients | % | Sex % | Mean age at diagnosis (years) | Mean delay to diagnosis (months) | Most common age group (years) | Most commonly involved Joints | Other Manifestations | Laboratory findings |
|---|---|---|---|---|---|---|---|---|---|---|
(I) 1981-1995 | Children's Hematology/Oncology Research Center | 54/1528 | 3.5 | M:62 F:38 | 7.3 | NA | 6-7 | Knee 68% Ankle52% | Organomegaly 83% Lymphadenopathy 76% | Anemia 59% Leukopenia 18% Leukocytosis 61% Thrombocytopenia 55% Raised ESR 37% |
(II) 1981-2003 | Â | 76/1832 | 4.1 | M:56.6 F:46.4 | 6.97 | NA | 5-7 | Knee 55% Ankle48% | NA | Anemia 88% Leukopenia 34% Leukocytosis 14% Thrombocytopenia 72% Raised ESR 58% Raised LDH 34% |
(III) 1996-2006 | Pediatric Rheumatology Center | 38/722 | 5.2 | M:52 F:48 | 5.6 | 2.7 | 5-7 | Hip 37% Knee 34% | Fever 73% Weight loss 60% Organomegaly 60% | Anemia 79% Leukopenia 45% Leukocytosis 16% Thrombocytopenia 63% |
(IV) 2006-2012 | Â | 11/207 | 5.3 | M:73 F:27 | 6.6 | 3 | 6-7 | Knee 45% Hip 27% | Fever 45% Organomegaly 27% | Anemia 27% Leukopenia 27% Leukocytosis 63% Thrombocytopenia 45% |