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Table 1

From: PReS-FINAL-2291: Activation of TLR pathway JSLE derived neutrophil extracellular traps

Cell Stimulation

dsDNA Concentration (ng)

Fold increase in pIRAK1 protein expression

Unstimulated PBMC

NA

0

Paediatric Control NET - IFN-α + IFN-α

0.2

33.7

1.9

2.1

JSLE NET - IFN-α + IFN-α

12.2

32.3

1.9

2.1

Adult Control NET + IFN-α

111.8

2.9