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Table 1

From: PReS-FINAL-2125: A Japanese girl with childhood-onset anti-Ku antibody positive generalized morphea-myositis overlap syndrome

 

Diagnosis

Initial

symptom

Age at onset,

Gender

Observation

period

Raynaud

phenomenon

Sclerodactyly

Myositis

Organ

involvement

CK(U/l)/

Ald(U/l)

ANA

clild

onset

GM/PM

Multiple skin lesions

7y

Female

8y6m

-

+

+

-

1,249/

20.9

1:1,280

adult

onset

DM

Muscle weakness,Weight loss

30y

Female

2y2m

+

-

+

IP

4,699/

53.8

1:2,560

 

SSc/PM

Muscle weakness, Joint pain

32y

Female

12y0m

+

+

+

ED

1,078/

16.6

1:10,240

 

SSc/PM

Arthritis

46y

Female

4y10m

+

+

+

IP,ED,

Arthritis

1,825/

30.9

1:640