Table 2 Baseline bone biopsies findings in 12 patients with IJO
Parameter | Median | Minimum | Maximum | Normal range (10–11) | |
|---|---|---|---|---|---|
Volume | Trabecular separation (Tb.Sp) (μm) | 432 | 367 | 610 | 299–587 |
Trabecular number (Tb.N) (#/mm) | 1.83 | 1.42 | 2.14 | 1.3–2.7 | |
Trabecular thickness (Tb.Th) (μm) | 107 | 79 | 145 | 72–177 | |
Bone volume (BV/TV) (%) | 19.71 | 13.61 | 26.8 | 9.3–22.7 | |
Mineralization | Mineral apposition rate (MAR) (μm/day) | 0.8 | 0.5 | 0.99 | 0.9–2.4 |
Mineralization lag time (MLT) (days) | 18.13 | 4.59 | 105.12 | 4.1–71.7 | |
Osteoid maturation time (OMT) (days) | 8.68 | 4.11 | 15.57 | 1.9–10.4 | |
Osteoid thickness (O.Th) (μm) | 6.92 | 2.73 | 9.61 | 3–13.9 | |
Osteoid volume (OV/BV) (%) | 1.21 | 0.26 | 4.65 | 0.2–5.86 | |
Osteoid surface (OS/BS) (%) | 8.69 | 3.15 | 30.39 | 1.4–23.96 | |
Turnover | Bone formation rate (BFR/BS) (μm2/mm3/year) | 12.81 | 1.95 | 78.91 | 10–73.4 |
Eroded surface (ES/BS) (%) | 4.28 | 0 | 13.27 | 1.6–6.84 |